安氟烷（CAS 13838-16-9）：分子式 C3H2ClF5O、分子量 184.49。
| CAS号 | 13838-16-9 |
|---|---|
| 分子式 | C3H2ClF5O |
| 分子量 | 184.49 |
| 熔点 | 48.5 |
| 沸点 | 134 °F at 760 mmHg (NIOSH, 2024) |
| LogP | 2.1 |
| 应用领域 | Uses: Stable inhalation anesthetic、[ChemIDplus]、MEDICATION、Used for the induction and maintenance of general anaesthesia during surgery and cesarean section and also used for analgesia during vaginal delivery.、Methods of Manufacturing: Enflurane is prepared by dichlorination of the methyl group of 1-chloro-1、2、2-trifluoro-2- methoxyethane and replacement of these two chlorine atoms by fluorine.、... Prepared by successive chlorination and fluorination of the hydrocarbon ether.、Formulations、Preparations: Enflurane、USP is packaged in 250 mL amber-colored bottles. (Piramal Critical Care Inc.)、General Manufacturing Information: Prepn: Terrell、GB patent 1、138、406、US patent 3、469、011、US patent 3527813 (1969、1969、1970 all to Air Reduction)、Fluorinated greenhouse gases (fluorinated GHGs) are man-made gases used in several sectors. They include hydrofluorocarbons (HFCs)、perfluorocarbons (PFCs)、sulfur hexafluoride (SF6)、nitrogen trifluoride (NF3)、and a number of fluorinated ethers. Fluorinated GHGs also include chlorofluorocarbons (CFCs) and hydrochlorofluorocarbons (HCFCs)、but these ozone-depleting substances (ODSs) are currently being phased out and otherwise regulated under the Montreal Protocol and Title VI of the Clean Air Act、and EPA is not proposing requirements for them under the GHG Reporting rule.、Fluorinated greenhouse gases |
登记用途：Uses: Stable inhalation anesthetic、[ChemIDplus]、MEDICATION、Used for the induction and maintenance of general anaesthesia during surgery and cesarean section and also used for analgesia during vaginal delivery.、Methods of Manufacturing: Enflurane is prepared by dichlorination of the methyl group of 1-chloro-1、2、2-trifluoro-2- methoxyethane and replacement of these two chlorine atoms by fluorine.、... Prepared by successive chlorination and fluorination of the hydrocarbon ether.、Formulations、Preparations: Enflurane、USP is packaged in 250 mL amber-colored bottles. (Piramal Critical Care Inc.)、General Manufacturing Information: Prepn: Terrell、GB patent 1、138、406、US patent 3、469、011、US patent 3527813 (1969、1969、1970 all to Air Reduction)、Fluorinated greenhouse gases (fluorinated GHGs) are man-made gases used in several sectors. They include hydrofluorocarbons (HFCs)、perfluorocarbons (PFCs)、sulfur hexafluoride (SF6)、nitrogen trifluoride (NF3)、and a number of fluorinated ethers. Fluorinated GHGs also include chlorofluorocarbons (CFCs) and hydrochlorofluorocarbons (HCFCs)、but these ozone-depleting substances (ODSs) are currently being phased out and otherwise regulated under the Montreal Protocol and Title VI of the Clean Air Act、and EPA is not proposing requirements for them under the GHG Reporting rule.、Fluorinated greenhouse gases。
安氟烷 是一种化工化合物，登记 CAS 号为 13838-16-9，分子式 C3H2ClF5O（分子量 184.49）。
登记 CAS 号：13838-16-9
其分子式 C3H2ClF5O 由 3 个碳、2 个氢、1 个氯、5 个氟、1 个氧 组成。
别名/同义词：安氟烷 · Enflurane
安氟烷 的 CAS 登记号为 13838-16-9。
分子式 C3H2ClF5O，分子量 184.49。
别名/同义词：安氟烷、Enflurane。
登记用途：Uses: Stable inhalation anesthetic、[ChemIDplus]、MEDICATION、Used for the induction and maintenance of general anaesthesia during surgery and cesarean section and also used for analgesia during vaginal delivery.、Methods of Manufacturing: Enflurane is prepared by dichlorination of the methyl group of 1-chloro-1、2、2-trifluoro-2- methoxyethane and replacement of these two chlorine atoms by fluorine.、... Prepared by successive chlorination and fluorination of the hydrocarbon ether.、Formulations、Preparations: Enflurane、USP is packaged in 250 mL amber-colored bottles. (Piramal Critical Care Inc.)、General Manufacturing Information: Prepn: Terrell、GB patent 1、138、406、US patent 3、469、011、US patent 3527813 (1969、1969、1970 all to Air Reduction)、Fluorinated greenhouse gases (fluorinated GHGs) are man-made gases used in several sectors. They include hydrofluorocarbons (HFCs)、perfluorocarbons (PFCs)、sulfur hexafluoride (SF6)、nitrogen trifluoride (NF3)、and a number of fluorinated ethers. Fluorinated GHGs also include chlorofluorocarbons (CFCs) and hydrochlorofluorocarbons (HCFCs)、but these ozone-depleting substances (ODSs) are currently being phased out and otherwise regulated under the Montreal Protocol and Title VI of the Clean Air Act、and EPA is not proposing requirements for them under the GHG Reporting rule.、Fluorinated greenhouse gases。
安氟烷（CAS 13838-16-9）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 13838-16-9 |
|---|---|
| PubChem CID | 3226 |
| Molecular formula | C3H2ClF5O |
| IUPAC name | 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane |
| UNII (FDA) | 91I69L5AY5 |
| Molecular Weight | 184.49 |
|---|---|
| XLogP3 | 2.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 3 |
| Exact Mass | 183.9714332 |
| Monoisotopic Mass | 183.9714332 |
| Topological Polar Surface Area | 9.2 |
| Heavy Atom Count | 10 |
| Boiling Point | 134 °F at 760 mmHg (NIOSH, 2024) |
|---|---|
| Boiling Point | 56.5 |
| Boiling Point | 56.5 °C |
| Boiling Point | 56 °C |
| Boiling Point | 134 °F |
| Melting Point | 48.5 |
| Solubility | In water, 5.62X10+3 mg/L at 25 °C |
| Solubility | 3.90e+00 g/L |
| Density | 1.5121 g/cu cm at 25 °C |
| Density | 1.52 at 77 °F |
enflurane; 13838-16-9; Methylflurether; 2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane; Efrane; Ethrane; 2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; Alyrane; Compound 347; Anesthetic 347; Anesthetic Compound No. 347; OHIO 347; Enflurano; Ethane, 2-chloro-1-(difluoromethoxy)-1,1,2-trifluoro-; Enfluranum; NSC-115944
| Reported hazard statements | H315 (54.2%), H319 (99%), H335 (54.2%), H332, H336, H361, H370, H316 |
|---|
H315 (54.2%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (99%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Enflurane · CAS 13838-16-9 · C3H2ClF5O. UNII 91I69L5AY5. Boiling Point: 134 °F at 760 mmHg (NIOSH, 2024); Boiling Point: 56.5; Boiling Point: 56.5 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Enflurane