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ethosuximide

CAS 77-67-8C7H11NO2MW 141.17

ethosuximide (CAS 77-67-8) — formula C7H11NO2, molecular weight 141.17; category pharmaceutical intermediates and APIs.

Product Description

ethosuximide (CAS 77-67-8) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C7H11NO2 comprises 7 C, 11 H, 1 N, 2 O atoms. Its molecular weight is about 141.17. Reported physicochemical data: melting point around 64.5, LogP about 0.38. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number77-67-8
Molecular FormulaC7H11NO2
Molecular Weight141.17
Melting Point64.5
LogP0.38
ApplicationsAntiepileptic, THERAP CAT: Anticonvulsant, MEDICATION, For the treatment of petit mal epilepsy, Pharmaceuticals, Methods of Manufacturing: The condensation of butanone with cyano ethyl acetate and subsequent reaction with NaCN and H2SO4 gives 2-ethyl-2-methyl-succinic acid
CategoryPharmaceutical Intermediates & APIs

Applications

Documented applications: Antiepileptic, THERAP CAT: Anticonvulsant, MEDICATION, For the treatment of petit mal epilepsy, Pharmaceuticals, Methods of Manufacturing: The condensation of butanone with cyano ethyl acetate and subsequent reaction with NaCN and H2SO4 gives 2-ethyl-2-methyl-succinic acid.

Technical Profile

What this product is

ethosuximide is a pharmaceutical intermediate or API compound with CAS registry number 77-67-8 and molecular formula C7H11NO2 (molecular weight 141.17), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Identification

CAS number: 77-67-8

Its molecular formula C7H11NO2 comprises 7 C, 11 H, 1 N, 2 O atoms.

Also known as: ethosuximide · 乙磺酰亚胺 · Petinimid

Category: pharmaceutical intermediates and APIs

Frequently Asked Questions

What is the CAS number of ethosuximide?

The CAS registry number of ethosuximide is 77-67-8.

What is the molecular formula and molecular weight of ethosuximide?

Molecular formula C7H11NO2, molecular weight 141.17.

What other names is ethosuximide known by?

It is also registered under: ethosuximide, 乙磺酰亚胺, Petinimid.

What are the documented applications of ethosuximide?

Recorded applications: Antiepileptic, THERAP CAT: Anticonvulsant, MEDICATION, For the treatment of petit mal epilepsy, Pharmaceuticals, Methods of Manufacturing: The condensation of butanone with cyano ethyl acetate and subsequent reaction with NaCN and H2SO4 gives 2-ethyl-2-methyl-succinic acid.

Which category does ethosuximide belong to?

Category: Pharmaceutical Intermediates & APIs.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for ethosuximide (CAS 77-67-8), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number77-67-8
PubChem CID3291
Molecular formulaC7H11NO2
IUPAC name3-ethyl-3-methylpyrrolidine-2,5-dione
UNII (FDA)5SEH9X1D1D

Computed descriptors

Molecular Weight141.17
XLogP30.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass141.078978594
Monoisotopic Mass141.078978594
Topological Polar Surface Area46.2
Heavy Atom Count10

Physicochemical values on record

Melting Point64.5
Melting Point64 - 65 °C
Melting Point64.5 °C
Solubility39.2
Solubility1.01e+02 g/L
LogP0.38
LogPlog Kow = 0.38
LogP0.1
LogP0.23

Documented uses on record

    For the treatment of petit mal epilepsy.The condensation of butanone with cyano ethyl acetate and subsequent reaction with NaCN and H2SO4 gives 2-ethyl-2-methyl-succinic acid, which is ring-closed via the diammonium salt to yield ethosuximide.

    Synonyms and trade names

    ethosuximide; 77-67-8; Zarontin; Etosuximida; 3-Ethyl-3-methylpyrrolidine-2,5-dione; 2-Ethyl-2-methylsuccinimide; Ethosuxide; Pyknolepsinum; Emeside; Suxilep; Ethosuccimide; Ethosuccinimide; Atysmal; Suxinutin; Etosuximid; Petinimid

    GHS hazard classification

    Reported hazard statementsH302 (95.7%)

    H302 (95.7%): Harmful if swallowed [Warning Acute toxicity, oral]

    P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)

    What the public record says

    Petinimid · CAS 77-67-8 · C7H11NO2. UNII 5SEH9X1D1D. Melting Point: 64.5; Melting Point: 64 - 65 °C; Melting Point: 64.5 °C.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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