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Eflornithine Hydrochloride

CAS 68278-23-9C6H12F2N2O2MW 182.17

Eflornithine Hydrochloride (CAS No. 68278-23-9) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Product Overview

CAS Number68278-23-9
Molecular FormulaC6H12F2N2O2
Molecular Weight182.17
Boiling Point347
LogP-2.9
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Applications

Pharmaceutical Intermediates & APIs

Packaging & Storage

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
ShippingStandard chemical transport
SampleAvailable on request
Lead TimeIn stock / per order

Quality & Documentation

COA (Certificate of Analysis) is provided with every batch. MSDS/technical data sheets and third-party test reports are available on request. Purity and packaging are subject to batch COA and order confirmation.

Frequently Asked Questions

What is the CAS number of Eflornithine Hydrochloride?

The CAS number of Eflornithine Hydrochloride is 68278-23-9.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Eflornithine Hydrochloride?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Eflornithine Hydrochloride or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Eflornithine Hydrochloride · CAS 68278-23-9 · C6H12F2N2O2. UNII ZQN1G5V6SR. Boiling Point: 347; Solubility: >10 mg/mL.

Identification

CAS Registry Number68278-23-9
PubChem CID3009
Molecular formulaC6H12F2N2O2
IUPAC name2,5-diamino-2-(difluoromethyl)pentanoic acid
UNII (FDA)ZQN1G5V6SR

Computed Descriptors

Molecular Weight182.17
XLogP3-2.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass182.08668395
Monoisotopic Mass182.08668395
Topological Polar Surface Area89.3
Heavy Atom Count12
Formal Charge0

Physical & Chemical Properties

Boiling Point347
Solubility>10 mg/mL

Physical description & handling notes

  • MW: 236.65 /Eflornithine hydrochloride/
  • Topical: Cream 13.9%, Veniqa (Skinmedica).

Documented Uses

  • Use (kg; approx.) in Germany (2009): >100
  • Consumption (g per capita; approx.) in Germany (2009): 0.00122
  • Eflornithine is indicated to reduce the risk of relapse in adult and pediatric patients with high-risk neuroblastoma (HRNB) who have demonstrated at least a partial response to prior multiagent, multimodality therapy including anti-GD2 immunotherapy. It was also previously indicated for the treatment of female hirsutism and African trypanosomiasis but has since been discontinued.
  • Breast Feeding; Lactation; Antiparasitic Agents; Antiprotozoal Agents; Enzyme Inhibitors; Trypanocidal Agents
  • Medicines for the treatment of 2nd stage African trypanosomiasis
  • Parenteral - General injections - IV: 200 mg per mL in 50 mL bottle (hydrochloride)

Synonyms

EFLORNITHINE; 70052-12-9; dfmo; 2-(Difluoromethyl)ornithine; 2,5-diamino-2-(difluoromethyl)pentanoic acid; Eflornitina; Eflornithinum; alpha-Difluoromethylornithine; 2-(Difluoromethyl)-DL-ornithine; alpha-(Difluoromethyl)-DL-ornithine; Ornithine, 2-(difluoromethyl)-; DL-alpha-Difluoromethylornithine; DL-Ornithine, 2-(difluoromethyl)-; ZQN1G5V6SR; CHEBI:41948; alpha,delta-Diamino-alpha-(difluoromethyl)valeric acid

Frequently Asked Questions

What are the CAS number and molecular formula of Eflornithine Hydrochloride?

CAS 68278-23-9; molecular formula C6H12F2N2O2; molecular weight — g/mol.

What other names is Eflornithine Hydrochloride known by?

EFLORNITHINE, 70052-12-9, dfmo, 2-(Difluoromethyl)ornithine, 2,5-diamino-2-(difluoromethyl)pentanoic acid, Eflornitina.

What are the key physical properties of Eflornithine Hydrochloride?

Boiling Point: 347; Solubility: >10 mg/mL.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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