乙硫异烟胺

Name: 乙硫异烟胺
Brand: 济南圣和化工有限公司

CAS 536-33-4C8H10N2SMW 166.25

济南圣和化工有限公司现供应医药中间体及原料药——乙硫异烟胺（CAS 536-33-4），分子式 C8H10N2S，分子量 166.25。本页理化参数仅供参考，实际常规纯度按批次COA提供(不公开发布)，以批次 COA 及订单确认为准，支持批量采购与长期供货协议。

产品概览

CAS号	536-33-4
分子式	C8H10N2S
分子量	166.25
熔点	166
LogP	0.5
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

该产品的下游应用集中在医药中间体及原料药。不同客户工艺差异较大，我们支持按需提供样品与小批量试用。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供货能力：乙硫异烟胺备有现货，包装形式为按订单/批次确认(不公开发布)。我们支持对公转账并开具增值税发票，山东省内可安排快速配送，省外按物流时效发货，具体请联系 info@591daili.com。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商，济南圣和化工有限公司长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除乙硫异烟胺外，您还可以在站内按 CAS 号或产品分类检索更多品类，获取规格与报价。

常见问题

乙硫异烟胺的 CAS 号是多少？

乙硫异烟胺的 CAS 号为 536-33-4。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

乙硫异烟胺有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

ethionamide · CAS 536-33-4 · C8H10N2S. UNII OAY8ORS3CQ. Melting Point: 166; Melting Point: 164-166 °C (decomposes); Melting Point: 163 °C.

Identification

CAS Registry Number	536-33-4
PubChem CID	2761171
Molecular formula	C8H10N2S
IUPAC name	2-ethylpyridine-4-carbothioamide
UNII (FDA)	OAY8ORS3CQ

Computed Descriptors

Molecular Weight	166.25
XLogP3	1.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	166.05646950
Monoisotopic Mass	166.05646950
Topological Polar Surface Area	71
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Melting Point	166
Melting Point	164-166 °C (decomposes)
Melting Point	163 °C
Solubility	8.39e-01 g/L
LogP	0.5
LogP	log Kow = 0.3699
LogP	1.52

Physical description & handling notes

Ethionamide appears as yellow crystals or canary yellow powder with a faint to moderate sulfide odor. (NTP, 1992)
Solid
Yellow crystals from ethanol
Faint to moderate sulfide odor
327 to 331 °F (Decomposes) (NTP, 1992)
less than 1 mg/mL at 70 °F (NTP, 1992)

GHS Hazard Classification

Reported hazard statements	H302 (95.7%), H361 (91.5%)

H302 (95.7%): Harmful if swallowed [Warning Acute toxicity, oral]

H361 (91.5%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

THERAP CAT: Antibacterial (tuberculostatic)
... Prepared by addition of hydrogen sulfide to 2-ethylnicotinonitrile in the presence of triethanolamine
For use in the treatment of pulmonary and extrapulmonary tuberculosis when other antitubercular drugs have failed.
Ethionamide is a second line drug in the therapy of tuberculosis used only in combination with other agents and for drug-resistant tuberculosis. Ethionamide has been linked to transient, asymptomatic elevations in serum aminotransferase levels and in uncommon instances of acute liver injury, which can be severe.
Breast Feeding; Lactation; Anti-infective Agents; Antitubercular Agents
(1) Oral - Solid - dispersible tablet: 125 mg; (2) Oral - Solid - tablet: 250 mg

Synonyms

ethionamide; 536-33-4; 2-ethylpyridine-4-carbothioamide; Trecator; Ethioniamide; Amidazine; Ethinamide; Ethyonomide; Etionamid; Etioniamid; 2-Ethylthioisonicotinamide; Nizotin; Ethylisothiamide; Teberus; Trecator-SC; Amidazin

Frequently Asked Questions

What are the CAS number and molecular formula of ethionamide?

CAS 536-33-4; molecular formula C8H10N2S; molecular weight — g/mol.

What other names is ethionamide known by?

ethionamide, 536-33-4, 2-ethylpyridine-4-carbothioamide, Trecator, Ethioniamide, Amidazine.

Is ethionamide classified as hazardous?

Hazard statements reported: H302, H361.

What are the key physical properties of ethionamide?

Melting Point: 166; Melting Point: 164-166 °C (decomposes); Melting Point: 163 °C; Solubility: 8.39e-01 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.