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erythromycin stearate

CAS 643-22-1C37H67NO13.C18H36O2MW 1018.4

erythromycin stearate (CAS 643-22-1) — formula C37H67NO13.C18H36O2, molecular weight 1018.4; category pharmaceutical intermediates and APIs.

Product Description

erythromycin stearate (CAS 643-22-1) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C37H67NO13.C18H36O2 comprises 55 C, 103 H, 1 N, 15 O atoms. Its molecular weight is about 1018.4. Reported physicochemical data: melting point around 212 to 219 °F (NTP, 1992). As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number643-22-1
Molecular FormulaC37H67NO13.C18H36O2
Molecular Weight1018.4
Melting Point212 to 219 °F (NTP, 1992)
ApplicationsFor use in the treatment of infections caused by susceptible strains of microorganisms in the following diseases: respiratory tract infections (upper and lower) of mild to moderate degree, pertussis (whooping cough), as adjunct to antitoxin in infections due to <i>Corynebacterium diphtheriae</i>, in the treatment of infections due to <i>Corynebacterium minutissimum</i>, intestinal amebiasis caused by <i>Entamoeba histolytica</i>, acute pelvic inflammatory disease caused by <i>Neisseria gonorrhoeae</i>
CategoryPharmaceutical Intermediates & APIs

Applications

Documented applications: For use in the treatment of infections caused by susceptible strains of microorganisms in the following diseases: respiratory tract infections (upper and lower) of mild to moderate degree, pertussis (whooping cough), as adjunct to antitoxin in infections due to <i>Corynebacterium diphtheriae</i>, in the treatment of infections due to <i>Corynebacterium minutissimum</i>, intestinal amebiasis caused by <i>Entamoeba histolytica</i>, acute pelvic inflammatory disease caused by <i>Neisseria gonorrhoeae</i>.

Technical Profile

What this product is

erythromycin stearate is a pharmaceutical intermediate or API compound with CAS registry number 643-22-1 and molecular formula C37H67NO13.C18H36O2 (molecular weight 1018.4), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Identification

CAS number: 643-22-1

Its molecular formula C37H67NO13.C18H36O2 comprises 55 C, 103 H, 1 N, 15 O atoms.

Also known as: erythromycin stearate · 硬脂酸红霉素

Category: pharmaceutical intermediates and APIs

Frequently Asked Questions

What is the CAS number of erythromycin stearate?

The CAS registry number of erythromycin stearate is 643-22-1.

What is the molecular formula and molecular weight of erythromycin stearate?

Molecular formula C37H67NO13.C18H36O2, molecular weight 1018.4.

What other names is erythromycin stearate known by?

It is also registered under: erythromycin stearate, 硬脂酸红霉素.

What are the documented applications of erythromycin stearate?

Recorded applications: For use in the treatment of infections caused by susceptible strains of microorganisms in the following diseases: respiratory tract infections (upper and lower) of mild to moderate degree, pertussis (whooping cough), as adjunct to antitoxin in infections due to <i>Corynebacterium diphtheriae</i>, in the treatment of infections due to <i>Corynebacterium minutissimum</i>, intestinal amebiasis caused by <i>Entamoeba histolytica</i>, acute pelvic inflammatory disease caused by <i>Neisseria gonorrhoeae</i>.

Which category does erythromycin stearate belong to?

Category: Pharmaceutical Intermediates & APIs.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for erythromycin stearate (CAS 643-22-1), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number643-22-1
PubChem CID12559
Molecular formulaC37H67NO13.C18H36O2
IUPAC name(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;octadecanoic acid
UNII (FDA)LXW024X05M

Computed descriptors

Molecular Weight1018.4
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count16
Rotatable Bond Count23
Exact Mass1017.73277158
Monoisotopic Mass1017.73277158
Topological Polar Surface Area231
Heavy Atom Count71

Physicochemical values on record

Melting Point212 to 219 °F (NTP, 1992)

Documented uses on record

    PREPN OF ERYTHROMCYIN STEARATE (ESTER) IS DESCRIBED IN BOOTH, MURRAY, US PATENT 2,862,921 (1958 TO UPJOHN).BY REACTING ERYTHROMYCIN WITH PROPER QUANT OF STEARIC ACID IN ACETONE SOLN & THEN DILUTING SOLN WITH WATER TO PPT SALT.

    Synonyms and trade names

    ERYTHROMYCIN STEARATE; 643-22-1; Abboticine; Bristamycin; Gallimycin; Erypar; Dowmycin E; Wyamycin S; Pfizer-E; Eratrex; Ethril; Meberyt; Erythrocin stearate; Erythromycin octadecanoate (salt); Sk-erythromycin; Ethril 250

    Regulatory listings held on file

    GHS notification summary0.9% (1 / 106)

    GHS hazard classification

    GHS notification summary0.9% (1 / 106)
    Reported hazard statementsH317 (59.4%), H319 (39.6%), H334 (59.4%)

    This chemical does not meet GHS hazard criteria for 0.9% (1 of 106) of reports.

    H317 (59.4%): May cause an allergic skin reaction [Warning Sensitization, Skin]

    What the public record says

    erythromycin stearate · CAS 643-22-1 · C37H67NO13.C18H36O2. UNII LXW024X05M. Melting Point: 212 to 219 °F (NTP, 1992).

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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Supplier: Jinan Shenghe Chemical Co., Ltd.

中文页面: 硬脂酸红霉素

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