✉ info@chemsp.cn☎ +86-18553102138 ☎ 0531-84992235
📞 WhatsApp中文
Home › Product Catalog › Dovitinib

Dovitinib

CAS 405169-16-6C21H21FN6OMW 392.4

Dovitinib (CAS 405169-16-6) — formula C21H21FN6O, molecular weight 392.4; category pharmaceutical intermediates and APIs.

Product Description

Dovitinib (CAS 405169-16-6) is a pharmaceutical intermediates and APIs. Its molecular formula C21H21FN6O comprises 21 C, 21 H, 1 F, 6 N, 1 O atoms. Its molecular weight is about 392.4. Reported physicochemical data: LogP about 1.6. Pharmaceutical intermediates and APIs are critical building blocks for drug synthesis, with strict requirements on purity, impurities and process consistency. Used in API synthesis, formulation and pre-clinical research; supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number405169-16-6
Molecular FormulaC21H21FN6O
Molecular Weight392.4
LogP1.6
Applicationsformulation and pre-clinical research, supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we can help locate and compare this item across domestic and cross-border channels, with COA and compliance files provided before ordering
CategoryPharmaceutical Intermediates & APIs

Applications

Documented applications: formulation and pre-clinical research, supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we can help locate and compare this item across domestic and cross-border channels, with COA and compliance files provided before ordering.

Technical Profile

What this product is

Dovitinib is a pharmaceutical intermediate or API compound with CAS registry number 405169-16-6 and molecular formula C21H21FN6O (molecular weight 392.4), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Identification

CAS number: 405169-16-6

Its molecular formula C21H21FN6O comprises 21 C, 21 H, 1 F, 6 N, 1 O atoms.

Also known as: Dovitinib · 多韦替尼

Category: pharmaceutical intermediates and APIs

Frequently Asked Questions

What is the CAS number of Dovitinib?

The CAS registry number of Dovitinib is 405169-16-6.

What is the molecular formula and molecular weight of Dovitinib?

Molecular formula C21H21FN6O, molecular weight 392.4.

What other names is Dovitinib known by?

It is also registered under: Dovitinib, 多韦替尼.

What are the documented applications of Dovitinib?

Recorded applications: formulation and pre-clinical research, supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we can help locate and compare this item across domestic and cross-border channels, with COA and compliance files provided before ordering.

Which category does Dovitinib belong to?

Category: Pharmaceutical Intermediates & APIs.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Dovitinib (CAS 405169-16-6), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number405169-16-6
PubChem CID135398510
Molecular formulaC21H21FN6O
IUPAC name4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one
UNII (FDA)I35H55G906

Computed descriptors

Molecular Weight392.4
XLogP31.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass392.17608748
Monoisotopic Mass392.17608748
Topological Polar Surface Area90.3
Heavy Atom Count29

Documented uses on record

  • Investigated for use/treatment in multiple myeloma and solid tumors.
  • Unlike many kinase inhibitors that only target vascular endothelial growth factor (VEGF), Dovitinib inhibits receptors in the fibroblast growth factor (FGF ) pathway, as well as VEGF and platelet-derived growth factor (PDGF). FGF receptor tyrosine kinase inhibition is potentially of therapeutic significance to a group of myeloma patients whose cancer cells express high levels of surface FGF receptors.

Synonyms and trade names

Dovitinib; 405169-16-6; TKI-258; I35H55G906; GFKI-258; 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-one; dovitinibum; 4-amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl)-1,2-dihydroquinolin-2-one; RefChem:590385; 4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one; Dovitinib [INN]; Chir 258; Dovitinib (TKI-258, CHIR-258); Dovitinib (TKI-258); Dovitinib lactate; 4-Amino-5-Fluoro-3-(6-(4-Methylpiperazin-1-yl)-1H-Benzo[D]Imidazol-2-yl)Quinolin-2(1H)-One

What the public record says

Dovitinib · CAS 405169-16-6 · C21H21FN6O. UNII I35H55G906.

Source: PubChem / Wikidata; the batch COA governs where values differ.

Request a Quote

✉ info@chemsp.cn☎ +86-18553102138📞 WhatsAppEmail InquiryWhatsApp Inquiry

Supplier: Jinan Shenghe Chemical Co., Ltd.

中文页面: 多韦替尼

Shenghe Chemical|ChemSP
鲁ICP备19037000号-2