Dacomitinib hydrate (CAS 1042385-75-0) — formula C24H27ClFN5O3, molecular weight 488.0; category pharmaceutical intermediates and APIs.
Dacomitinib hydrate (CAS 1042385-75-0) is a pharmaceutical intermediates and APIs. Its molecular formula C24H27ClFN5O3 comprises 24 C, 27 H, 1 Cl, 1 F, 5 N, 3 O atoms. Its molecular weight is about 488.0. Pharmaceutical intermediates and APIs are critical building blocks for drug synthesis, with strict requirements on purity, impurities and process consistency. Used in API synthesis, formulation and pre-clinical research; supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 1042385-75-0 |
|---|---|
| Molecular Formula | C24H27ClFN5O3 |
| Molecular Weight | 488.0 |
| Applications | formulation and pre-clinical research, supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we can help locate and compare this item across domestic and cross-border channels, with COA and compliance files provided before ordering |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: formulation and pre-clinical research, supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we can help locate and compare this item across domestic and cross-border channels, with COA and compliance files provided before ordering.
Dacomitinib hydrate is a pharmaceutical intermediate or API compound with CAS registry number 1042385-75-0 and molecular formula C24H27ClFN5O3 (molecular weight 488.0), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 1042385-75-0
Its molecular formula C24H27ClFN5O3 comprises 24 C, 27 H, 1 Cl, 1 F, 5 N, 3 O atoms.
Also known as: Dacomitinib hydrate · 达克替尼水合物
Category: pharmaceutical intermediates and APIs
The CAS registry number of Dacomitinib hydrate is 1042385-75-0.
Molecular formula C24H27ClFN5O3, molecular weight 488.0.
It is also registered under: Dacomitinib hydrate, 达克替尼水合物.
Recorded applications: formulation and pre-clinical research, supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we can help locate and compare this item across domestic and cross-border channels, with COA and compliance files provided before ordering.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Dacomitinib hydrate (CAS 1042385-75-0), compiled from public chemistry databases.
| CAS Registry Number | 1042385-75-0 |
|---|---|
| PubChem CID | 70693519 |
| Molecular formula | C24H27ClFN5O3 |
| IUPAC name | (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide;hydrate |
| UNII (FDA) | 5092U85G58 |
| Molecular Weight | 488.0 |
|---|---|
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 7 |
| Exact Mass | 487.1786456 |
| Monoisotopic Mass | 487.1786456 |
| Topological Polar Surface Area | 80.4 |
| Heavy Atom Count | 34 |
Dacomitinib monohydrate; DACOMITINIB HYDRATE; (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide hydrate; Dacomitinib Monhydrate; Dacomitinib (hydrate); Dacomitinib [USAN:INN]; Dacomitinib (USAN); Dacomitinib [USAN]; Dacomitinib hydrate (JAN); (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide;hydrate; DACOMITINIB HYDRATE [JAN]; PF 00299804; UNII-5092U85G58; Vizimpro (TN); PF299804 hydrate; DACOMITINIB [MI]
Dacomitinib hydrate · CAS 1042385-75-0 · C24H27ClFN5O3. UNII 5092U85G58.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 达克替尼水合物