Dexrazoxane hydrochloride

CAS 149003-01-0C11H17ClN4O4MW 304.73

Dexrazoxane hydrochloride (CAS 149003-01-0) — formula C11H17ClN4O4, molecular weight 304.73.

Product Overview

CAS Number	149003-01-0
Molecular Formula	C11H17ClN4O4
Molecular Weight	304.73
Applications	Uses: For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin hydrochloride dose of 300 mg, m^2 and would benefit from continued doxorubicin therapy. Also approved for the treatment of extravasation from intravenous anthracyclines.

Applications

Documented applications: Uses: For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin hydrochloride dose of 300 mg, m^2 and would benefit from continued doxorubicin therapy. Also approved for the treatment of extravasation from intravenous anthracyclines..

Technical Profile

What this product is

Dexrazoxane hydrochloride is a chemical compound with CAS registry number 149003-01-0 and molecular formula C11H17ClN4O4 (molecular weight 304.73).

Identification

CAS number: 149003-01-0

Its molecular formula C11H17ClN4O4 comprises 11 C, 17 H, 1 Cl, 4 N, 4 O atoms.

Also known as: Dexrazoxane hydrochloride · 盐酸右雷佐生

Frequently Asked Questions

What is the CAS number of Dexrazoxane hydrochloride?

The CAS registry number of Dexrazoxane hydrochloride is 149003-01-0.

What is the molecular formula and molecular weight of Dexrazoxane hydrochloride?

Molecular formula C11H17ClN4O4, molecular weight 304.73.

What other names is Dexrazoxane hydrochloride known by?

It is also registered under: Dexrazoxane hydrochloride, 盐酸右雷佐生.

What are the documented applications of Dexrazoxane hydrochloride?

Recorded applications: Uses: For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin hydrochloride dose of 300 mg, m^2 and would benefit from continued doxorubicin therapy. Also approved for the treatment of extravasation from intravenous anthracyclines..

PubChem Public Data

Independent reference data for Dexrazoxane hydrochloride (CAS 149003-01-0), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number	149003-01-0
PubChem CID	6918223
Molecular formula	C11H17ClN4O4
IUPAC name	4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride
UNII (FDA)	5346058Q7S

Computed descriptors

Molecular Weight	304.73
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	304.0938327
Monoisotopic Mass	304.0938327
Topological Polar Surface Area	98.8
Heavy Atom Count	20

Documented uses on record

Synonyms and trade names

Dexrazoxane hydrochloride; 149003-01-0; Dexrazoxane HCl; Cardioxane; Totect; Cardioxan; Savene; 1263283-43-7; ADR-529 hydrochloride; ICRF-187 hydrochloride; (+)-Razoxane hydrochloride; Razoxane hydrochloride, (S)-; 2,6-Piperazinedione, 4,4'-((1S)-1-methyl-1,2-ethanediyl)bis-, hydrochloride (1:1); 5346058Q7S; Razoxane (+)-form hydrochloride; DTXSID60164152

What the public record says

Dexrazoxane hydrochloride · CAS 149003-01-0 · C11H17ClN4O4. UNII 5346058Q7S.

Source: PubChem / Wikidata; the batch COA governs where values differ.