达洛鲁胺

Name: 达洛鲁胺
Brand: 济南圣和化工有限公司

CAS 1297538-32-9C19H19ClN6O2MW 398.8

本页收录达洛鲁胺，CAS 登记号为 1297538-32-9，分子式 C19H19ClN6O2，分子量 398.8，归类于医药中间体及原料药。作为主营产品之一，济南圣和化工有限公司可提供从公斤级到吨级的稳定供货，随货附 COA 与质检资料。

产品概览

CAS号	1297538-32-9
分子式	C19H19ClN6O2
分子量	398.8
沸点	719.5±60.0
LogP	1.904
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

达洛鲁胺在医药中间体及原料药领域使用广泛。采购前请确认纯度等级与包装形式，以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供货能力：达洛鲁胺备有现货，包装形式为按订单/批次确认(不公开发布)。我们支持对公转账并开具增值税发票，山东省内可安排快速配送，省外按物流时效发货，具体请联系 info@591daili.com。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

济南圣和化工有限公司位于山东济南，主营化工原料供应，精选产品 3,000+ 种，覆盖有机化学品、无机化学品、食品添加剂、医药中间体等 12 大分类。我们随货提供 COA 分析证书，一个工作日内回复报价，欢迎国内外采购方长期合作。

常见问题

达洛鲁胺的 CAS 号是多少？

达洛鲁胺的 CAS 号为 1297538-32-9。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

达洛鲁胺有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Darolutamide · CAS 1297538-32-9 · C19H19ClN6O2. UNII X05U0N2RCO. Boiling Point: 719.5±60.0; LogP: 1.904; Dissociation Constants: 11.75.

Identification

CAS Registry Number	1297538-32-9
PubChem CID	67171867
Molecular formula	C19H19ClN6O2
IUPAC name	N-[(2S)-1-[3-(3-chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
UNII (FDA)	X05U0N2RCO

Computed Descriptors

Molecular Weight	398.8
XLogP3	1.8
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	398.1258016
Monoisotopic Mass	398.1258016
Topological Polar Surface Area	120
Heavy Atom Count	28
Formal Charge	0

Physical & Chemical Properties

Boiling Point	719.5±60.0
LogP	1.904
Dissociation Constants	11.75

Physical description & handling notes

Darolutamide, through its downstream effects on cancer cell growth, treats castrate-resistant prostate cancer. It inhibits cancer cell growth and markedly lowers prostate specific antigen (PSA) levels through potent androgen receptor antagonism.

GHS Hazard Classification

Reported hazard statements	H302 (100%), H400 (100%), H410 (100%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

Documented Uses

Darolutamide is indicated for the treatment of adults with non-metastatic castration-resistant prostate cancer (nmCRPC) and metastatic castration-sensitive prostate cancer (mCSPC), either as monotherapy or in combination with docetaxel.
Darolutamide is a third generation, oral nonsteroidal antiandrogen used to treat nonmetastatic castration-resistant prostate cancer. Darolutamide is associated with a low rate of serum enzyme elevation during therapy, but has not been linked to cases of clinically apparent liver injury with jaundice.
Darolutamide is approved to treat:
• Prostate cancer. It is used in adults whose cancer:
• Has spread to other parts of the body and responds to treatment that lowers testosterone levels. It is used alone or with docetaxel.
• Has not spread to other parts of the body and no longer responds to treatment that lowers testosterone levels.

Synonyms

Darolutamide; 1297538-32-9; ODM-201; Nubeqa; BAY1841788; BAY-1841788; darolutamida; X05U0N2RCO; BAY 1841788; N-[(2S)-1-[3-(3-chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide; DTXSID101027953; darolutamidum; N-((2S)-1-(3-(3-chloro-4-cyanophenyl)pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide; Antiandrogen ODM-201; RefChem:58141; L02BB06

Frequently Asked Questions

What are the CAS number and molecular formula of Darolutamide?

CAS 1297538-32-9; molecular formula C19H19ClN6O2; molecular weight — g/mol.

What other names is Darolutamide known by?

Darolutamide, 1297538-32-9, ODM-201, Nubeqa, BAY1841788, BAY-1841788.

Is Darolutamide classified as hazardous?

Hazard statements reported: H302, H400, H410.

What are the key physical properties of Darolutamide?

Boiling Point: 719.5±60.0; LogP: 1.904; Dissociation Constants: 11.75.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.