Dasatinib monohydrate (CAS 863127-77-9) — formula C22H26ClN7O2S, molecular weight 488.0; category pharmaceutical intermediates and APIs.
Dasatinib monohydrate (CAS 863127-77-9) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C22H26ClN7O2S comprises 22 C, 26 H, 1 Cl, 7 N, 2 O, 1 S atoms. Its molecular weight is about 488.0. Reported physicochemical data: melting point around 280-286 °C, LogP about 1.8. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 863127-77-9 |
|---|---|
| Molecular Formula | C22H26ClN7O2S |
| Molecular Weight | 488.0 |
| Melting Point | 280-286 °C |
| LogP | 1.8 |
| Applications | Use (kg, approx.) in Germany (2009): >10, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Calculated removal (%): 1.9 |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: Use (kg, approx.) in Germany (2009): >10, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Calculated removal (%): 1.9.
Dasatinib monohydrate is a pharmaceutical intermediate or API compound with CAS registry number 863127-77-9 and molecular formula C22H26ClN7O2S (molecular weight 488.0), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 863127-77-9
Its molecular formula C22H26ClN7O2S comprises 22 C, 26 H, 1 Cl, 7 N, 2 O, 1 S atoms.
Also known as: Dasatinib monohydrate · 达沙替尼一水合物
Category: pharmaceutical intermediates and APIs
The CAS registry number of Dasatinib monohydrate is 863127-77-9.
Molecular formula C22H26ClN7O2S, molecular weight 488.0.
It is also registered under: Dasatinib monohydrate, 达沙替尼一水合物.
Recorded applications: Use (kg, approx.) in Germany (2009): >10, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Calculated removal (%): 1.9.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Dasatinib monohydrate (CAS 863127-77-9), compiled from public chemistry databases.
| CAS Registry Number | 863127-77-9 |
|---|---|
| PubChem CID | 3062316 |
| Molecular formula | C22H26ClN7O2S |
| IUPAC name | N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide |
| UNII (FDA) | X78UG0A0RN |
| Molecular Weight | 488.0 |
|---|---|
| XLogP3 | 3.6 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 7 |
| Exact Mass | 487.1557220 |
| Monoisotopic Mass | 487.1557220 |
| Topological Polar Surface Area | 135 |
| Heavy Atom Count | 33 |
| Melting Point | 280-286 °C |
|---|---|
| Melting Point | 280 - 286 °C |
| Solubility | 1.28e-02 g/L |
| LogP | 1.8 |
| LogP | 3.41 |
Dasatinib; 302962-49-8; Sprycel; BMS-354825; Dasatinib anhydrous; BMS354825; Dasatinib (anhydrous); BMS 354825; dasatinibum; anh. dasatinib; anhydrous dasatinib; dasatinib (anh.); DTXSID4040979; BMS Dasatinib; X78UG0A0RN; NSC732517
| Reported hazard statements | H301 (92.5%), H315 (77.5%), H318 (75%), H351 (80%), H360 (12.5%), H361 (80%), H371 (10%), H372 (80%) |
|---|
H301 (92.5%): Toxic if swallowed [Danger Acute toxicity, oral]
H315 (77.5%): Causes skin irritation [Warning Skin corrosion/irritation]
Dasatinib monohydrate · CAS 863127-77-9 · C22H26ClN7O2S. UNII X78UG0A0RN. Melting Point: 280-286 °C; Melting Point: 280 - 286 °C; Solubility: 1.28e-02 g/L.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 达沙替尼一水合物