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德克拉伐替尼 (BMS-986165)

CAS 1609392-27-9C20H22N8O3MW 425.5

济南圣和化工主营供应 德克拉伐替尼 (BMS-986165)(CAS 1609392-27-9),归类于医药原料,分子式 C20H22N8O3,分子量 425.5。我们面向国内化工贸易与生产企业提供稳定的现货供应,报价响应快,支持对公转账并可开具增值税发票。

产品概览

CAS号1609392-27-9
分子式C20H22N8O3
分子量425.5
LogP1.2
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域医药原料;医药中间体及原料药
类别医药原料|医药中间体及原料药

应用领域

医药原料;医药中间体及原料药

在下游生产中,医药原料是 德克拉伐替尼 (BMS-986165) 最主要的应用场景;此外它还用于医药中间体及原料药。若您有特定工艺要求,可在询价时注明用途,我们会推荐匹配的纯度等级。

包装与储存

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

采购提示:本产品按按订单/批次确认(不公开发布)起订发货,收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存;如需 MSDS 或运输说明,可在询价时一并索取。

质量与文件

每批产品随货提供 COA(分析证书);可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择 济南圣和化工有限公司 的理由:产品信息透明(含 CAS、分子式、理化参数)、报价响应快(一个工作日内)、单证齐全(COA/MSS/质检资料按需提供)、支持批量与长期协议供货。如需 德克拉伐替尼 (BMS-986165) 以外的配套原料,也欢迎一并列出需求清单。

常见问题

德克拉伐替尼 (BMS-986165) 的 CAS 号是多少?

德克拉伐替尼 (BMS-986165) 的 CAS 号为 1609392-27-9。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

德克拉伐替尼 (BMS-986165) 有什么用途?

主要应用于医药原料;医药中间体及原料药。

如何购买或获取报价?

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系,注明产品名称、CAS 号与需求数量,一个工作日内回复报价。供应商:济南圣和化工有限公司。

PubChem 公开数据

Description

Deucravacitinib (BMS-986165) · CAS 1609392-27-9 · C20H22N8O3. UNII N0A21N6RAU.

Identification

CAS Registry Number1609392-27-9
PubChem CID134821691
Molecular formulaC20H22N8O3
IUPAC name6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-(1-methyl-1,2,4-triazol-3-yl)anilino]-N-(trideuteriomethyl)pyridazine-3-carboxamide
UNII (FDA)N0A21N6RAU

Computed Descriptors

Molecular Weight425.5
XLogP31.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass425.20031683
Monoisotopic Mass425.20031683
Topological Polar Surface Area136
Heavy Atom Count31
Formal Charge0

Regulatory Status

GHS notification summary33.3% (1 / 3)

GHS Hazard Classification

GHS notification summary33.3% (1 / 3)
Reported hazard statementsH361 (33.3%), H372 (66.7%)

This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.

H361 (33.3%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

  • Deucravacitinib is a tyrosine kinase 2 (TYK2) inhibitor indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. It is not recommended for use in combination with other potent immunosuppressants. It is also indicated for the treatment of psoriatic arthritis in adults.
  • Deucravacitinib is a small molecule inhibitor of tyrosine kinase 2 that is used in the treatment of moderate-to-severe plaque psoriasis. Deucravacitinib is associated with transient and usually mild elevations in serum aminotransferase levels during therapy but has not been linked instances of clinically apparent acute liver injury.
  • Breast Feeding; Lactation; Milk, Human; Dermatologic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors; Tyrosine Kinase Inhibitors; Signal Transduction Inhibitors; Janus Kinase Inhibitors; JAK Inhibitors
  • Take with or without food. Food has no clinically significant effect on drug absorption and exposure.
  • Drugs used to treat or prevent skin disorders or for the routine care of skin.
  • Protein kinase inhibitors that inhibit TYROSINE PROTEIN KINASES.

Synonyms

Deucravacitinib; 1609392-27-9; BMS-986165; Sotyktu; N0A21N6RAU; RefChem:58358; Tyk2-IN-4; BMS986165; Deucravacitinib [USAN]; MFCD31715455; Deucravacitinib (BMS-986165); Tyk2-IN-4(BMS986165); bms 986165; Sotyktu (TN); Deucravacitinib [MI]; UNII-N0A21N6RAU

Frequently Asked Questions

What are the CAS number and molecular formula of Deucravacitinib (BMS-986165)?

CAS 1609392-27-9; molecular formula C20H22N8O3; molecular weight — g/mol.

What other names is Deucravacitinib (BMS-986165) known by?

Deucravacitinib, 1609392-27-9, BMS-986165, Sotyktu, N0A21N6RAU, RefChem:58358.

Is Deucravacitinib (BMS-986165) classified as hazardous?

33.3% of GHS notifications report no hazard classification (1 of 3).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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