doripenem

Description

doripenem · CAS 148016-81-3 · C15H24N4O6S2. UNII BHV525JOBH.

Identification

Computed Descriptors

Physical description & handling notes

• Similar to other beta-lactam antimicrobial agents, the time that unbound plasma concentration of doripenem exceeds the MIC (T>MIC) of the infecting organism has been shown to best correlate with efficacy in animal models of infection.

Documented Uses

• Use (kg; approx.) in Germany (2009): >10
• Consumption (g per capita; approx.) in Germany (2009): 0.000122
• Doripenem is indicated in the treatment of complicated intra-abdominal infections and complicated urinary tract infections, including pyelonephritis, caused by designated susceptible bacteria.
• Doripenem is a broad spectrum carbapenem antibiotic used primarily for the treatment of aerobic gram-negative bacterial infections. Doripenem, like other carbapenems, is associated with transient and asymptomatic elevations in serum enzymes. The carbapenems have also been linked to rare instances of clinically apparent, acute cholestatic liver injury.
• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antibacterial Agents; Carbapenems
• Substances that inhibit the growth or reproduction of BACTERIA.

Synonyms

Doripenem; 148016-81-3; Doribax; S-4661; Finibax; DTXSID2046678; BHV525JOBH; DTXCID0026678; doripenemum; RefChem:56365; J01DH04; S4661; MFCD02092739; S 4661; NCGC00167510-01; C15H24N4O6S2

Frequently Asked Questions

What are the CAS number and molecular formula of doripenem?

CAS 148016-81-3; molecular formula C15H24N4O6S2; molecular weight — g/mol.

What other names is doripenem known by?

Doripenem, 148016-81-3, Doribax, S-4661, Finibax, DTXSID2046678.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.