Dexrazoxane (CAS 24584-09-6) — formula C11H16N4O4, molecular weight 268.27; category dyes and pigments.
Dexrazoxane (CAS 24584-09-6) is a chemical raw material in the dyes and pigments category. Its molecular formula C11H16N4O4 comprises 11 C, 16 H, 4 N, 4 O atoms. Its molecular weight is about 268.27. Reported physicochemical data: melting point around 191-197 °C, LogP about -1.4. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 24584-09-6 |
|---|---|
| Molecular Formula | C11H16N4O4 |
| Molecular Weight | 268.27 |
| Melting Point | 191-197 °C |
| LogP | -1.4 |
| Applications | Cardioprotective agent, For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin hydrochloride dose of 300 mg/m^2 and would benefit from continued doxorubicin therapy. Also approved for the treatment of extravasation from intravenous anthracyclines, Methods of Manufacturing: Preparation: A. M. Creighton, GB 1234935 eidem, US 3941790 (1971, 1976 both to Natl. Res. Dev. Corp.) |
| Category | Dyes & Pigments |
Documented applications: Cardioprotective agent, For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin hydrochloride dose of 300 mg/m^2 and would benefit from continued doxorubicin therapy. Also approved for the treatment of extravasation from intravenous anthracyclines, Methods of Manufacturing: Preparation: A. M. Creighton, GB 1234935 eidem, US 3941790 (1971, 1976 both to Natl. Res. Dev. Corp.).
Dexrazoxane is a colorant or pigment compound with CAS registry number 24584-09-6 and molecular formula C11H16N4O4 (molecular weight 268.27), belonging to the dyes and pigments segment of chemical raw materials.
CAS number: 24584-09-6
Its molecular formula C11H16N4O4 comprises 11 C, 16 H, 4 N, 4 O atoms.
Also known as: Dexrazoxane · 右雷佐生
Category: dyes and pigments
The CAS registry number of Dexrazoxane is 24584-09-6.
Molecular formula C11H16N4O4, molecular weight 268.27.
It is also registered under: Dexrazoxane, 右雷佐生.
Recorded applications: Cardioprotective agent, For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin hydrochloride dose of 300 mg/m^2 and would benefit from continued doxorubicin therapy. Also approved for the treatment of extravasation from intravenous anthracyclines, Methods of Manufacturing: Preparation: A. M. Creighton, GB 1234935 eidem, US 3941790 (1971, 1976 both to Natl. Res. Dev. Corp.).
Category: Dyes & Pigments.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Dexrazoxane (CAS 24584-09-6), compiled from public chemistry databases.
| CAS Registry Number | 24584-09-6 |
|---|---|
| PubChem CID | 71384 |
| Molecular formula | C11H16N4O4 |
| IUPAC name | 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione |
| UNII (FDA) | 048L81261F |
| Molecular Weight | 268.27 |
|---|---|
| XLogP3 | -1.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 3 |
| Exact Mass | 268.11715500 |
| Monoisotopic Mass | 268.11715500 |
| Topological Polar Surface Area | 98.8 |
| Heavy Atom Count | 19 |
| Melting Point | 191-197 °C |
|---|---|
| Melting Point | 193 °C |
| Melting Point | 191 - 197 °C |
| Solubility | In water, 10-12 mg/mL at 25 °C |
| Solubility | 1.04e+01 g/L |
| Solubility | H2O 10 - 12 (mg/mL) |
| Solubility | 0.1 N HCI 35 - 43 (mg/mL) |
| Solubility | 0.1 N NaOH 25 - 34 (mg/mL) |
| Solubility | 10% EtOH 6.7 - 10 (mg/mL) |
| Solubility | MeOH 1 (mg/mL) |
Dexrazoxane; 24584-09-6; Dextrorazoxane; Dexrazoxano; ICRF-187; Dexrazoxanum; ADR-529; Razoxane, d-; 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione; Razoxane, (s)-; (+)-(S)-4,4'-Propylenedi-2,6-piperazinedione; ADR 529; ICRF 187; (+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane; NSC-169780; NSC 169780
| Reported hazard statements | H315 (97.7%), H319 (97.7%), H335 (95.3%) |
|---|
H315 (97.7%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (97.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Dexrazoxane · CAS 24584-09-6 · C11H16N4O4. UNII 048L81261F. Melting Point: 191-197 °C; Melting Point: 193 °C; Melting Point: 191 - 197 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 右雷佐生