desipramine (CAS 50-47-5) — formula C18H22N2, molecular weight 266.4; category pharmaceutical intermediates and APIs.
desipramine (CAS 50-47-5) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C18H22N2 comprises 18 C, 22 H, 2 N atoms. Its molecular weight is about 266.4. Reported physicochemical data: melting point around 214-218 °C, boiling point around 172-174 °C @ 0.02 MM HG, LogP about 4.9. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 50-47-5 |
|---|---|
| Molecular Formula | C18H22N2 |
| Molecular Weight | 266.4 |
| Melting Point | 214-218 °C |
| Boiling Point | 172-174 °C @ 0.02 MM HG |
| LogP | 4.9 |
| Applications | Antidepressant, For relief of symptoms in various depressive syndromes, especially endogenous depression. It has also been used to manage chronic peripheral neuropathic pain, as a second line agent for the management of anxiety disorders (e.g. panic disorder, generalized anxiety disorder), and as a second or third line agent in the ADHD management |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: Antidepressant, For relief of symptoms in various depressive syndromes, especially endogenous depression. It has also been used to manage chronic peripheral neuropathic pain, as a second line agent for the management of anxiety disorders (e.g. panic disorder, generalized anxiety disorder), and as a second or third line agent in the ADHD management.
desipramine is a pharmaceutical intermediate or API compound with CAS registry number 50-47-5 and molecular formula C18H22N2 (molecular weight 266.4), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 50-47-5
Its molecular formula C18H22N2 comprises 18 C, 22 H, 2 N atoms.
Also known as: desipramine · 地昔帕明
Category: pharmaceutical intermediates and APIs
The CAS registry number of desipramine is 50-47-5.
Molecular formula C18H22N2, molecular weight 266.4.
It is also registered under: desipramine, 地昔帕明.
Recorded applications: Antidepressant, For relief of symptoms in various depressive syndromes, especially endogenous depression. It has also been used to manage chronic peripheral neuropathic pain, as a second line agent for the management of anxiety disorders (e.g. panic disorder, generalized anxiety disorder), and as a second or third line agent in the ADHD management.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for desipramine (CAS 50-47-5), compiled from public chemistry databases.
| CAS Registry Number | 50-47-5 |
|---|---|
| PubChem CID | 2995 |
| Molecular formula | C18H22N2 |
| IUPAC name | 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine |
| UNII (FDA) | TG537D343B |
| Molecular Weight | 266.4 |
|---|---|
| XLogP3 | 4.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 4 |
| Exact Mass | 266.178298710 |
| Monoisotopic Mass | 266.178298710 |
| Topological Polar Surface Area | 15.3 |
| Heavy Atom Count | 20 |
| Boiling Point | 172-174 °C @ 0.02 MM HG |
|---|---|
| Melting Point | 214-218 °C |
| Melting Point | 214 - 218 °C |
| Solubility | 58.6 |
| Solubility | In water, 58.6 mg/l @ 24 °C. |
| Solubility | 3.96e-02 g/L |
| LogP | 4.9 |
| LogP | log Kow = 4.90 |
| LogP | 3.7 |
| LogP | 4.0 |
desipramine; Norimipramine; 50-47-5; Desmethylimipramine; Monodemethylimipramine; Desipramin; Demethylimipramine; Desimipramine; Dimethylimipramine; Dezipramine; Desipramina; Methylaminopropyliminodibenzyl; Imipramine, demethyl-; desipraminum; Desimpramine; 3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE
| Reported hazard statements | H302 (66.7%), H336 (66.7%), H370 (66.7%), H400 (33.3%) |
|---|
H302 (66.7%): Harmful if swallowed [Warning Acute toxicity, oral]
H336 (66.7%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]
desipramine · CAS 50-47-5 · C18H22N2. UNII TG537D343B. Boiling Point: 172-174 °C @ 0.02 MM HG; Melting Point: 214-218 °C; Melting Point: 214 - 218 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 地昔帕明