Doxazosin (CAS 74191-85-8) — formula C23H25N5O5, molecular weight 451.5; category pharmaceutical intermediates and APIs.
Doxazosin (CAS 74191-85-8) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C23H25N5O5 comprises 23 C, 25 H, 5 N, 5 O atoms. Its molecular weight is about 451.5. Reported physicochemical data: melting point around 275-277, boiling point around 718, LogP about 2.1. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 74191-85-8 |
|---|---|
| Molecular Formula | C23H25N5O5 |
| Molecular Weight | 451.5 |
| Melting Point | 275-277 |
| Boiling Point | 718 |
| LogP | 2.1 |
| Applications | Use (kg, approx.) in Germany (2009): >250, Use (kg) in USA (2002): 420, Consumption (g per capita, approx.) in Germany (2009): 0.00305, Consumption (g per capita) in the USA (2002): 0.00149 |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: Use (kg, approx.) in Germany (2009): >250, Use (kg) in USA (2002): 420, Consumption (g per capita, approx.) in Germany (2009): 0.00305, Consumption (g per capita) in the USA (2002): 0.00149.
Doxazosin is a pharmaceutical intermediate or API compound with CAS registry number 74191-85-8 and molecular formula C23H25N5O5 (molecular weight 451.5), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 74191-85-8
Its molecular formula C23H25N5O5 comprises 23 C, 25 H, 5 N, 5 O atoms.
Also known as: Doxazosin · 多沙唑嗪
Category: pharmaceutical intermediates and APIs
The CAS registry number of Doxazosin is 74191-85-8.
Molecular formula C23H25N5O5, molecular weight 451.5.
It is also registered under: Doxazosin, 多沙唑嗪.
Recorded applications: Use (kg, approx.) in Germany (2009): >250, Use (kg) in USA (2002): 420, Consumption (g per capita, approx.) in Germany (2009): 0.00305, Consumption (g per capita) in the USA (2002): 0.00149.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Doxazosin (CAS 74191-85-8), compiled from public chemistry databases.
| CAS Registry Number | 74191-85-8 |
|---|---|
| PubChem CID | 3157 |
| Molecular formula | C23H25N5O5 |
| IUPAC name | [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone |
| UNII (FDA) | NW1291F1W8 |
| Molecular Weight | 451.5 |
|---|---|
| XLogP3 | 2.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 4 |
| Exact Mass | 451.18556891 |
| Monoisotopic Mass | 451.18556891 |
| Topological Polar Surface Area | 112 |
| Heavy Atom Count | 33 |
| Boiling Point | 718 |
|---|---|
| Melting Point | 275-277 |
| Melting Point | 289 - 290 °C |
| Solubility | 0.8% |
| Solubility | 7.90e-01 g/L |
| LogP | 2.1 |
| LogP | 3.38 |
| Dissociation Constants | 6.52 |
doxazosin; 74191-85-8; Doxazosine; Doxazosinum; Doxazosina; UK-33274; C02CA04; 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin; CHEBI:4708; UK 33274; 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin; DTXSID7022964; NW1291F1W8; Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl)-; 2-{4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine; (4-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-1-PIPERAZINYL)(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YL)METHANONE
| Reported hazard statements | H302 (20%), H314 (80%), H373 (80%), H411 (80%) |
|---|
H302 (20%): Harmful if swallowed [Warning Acute toxicity, oral]
H314 (80%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
Doxazosin · CAS 74191-85-8 · C23H25N5O5. UNII NW1291F1W8. Boiling Point: 718; Melting Point: 275-277; Melting Point: 289 - 290 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 多沙唑嗪