去氧孕烯（CAS 54024-22-5）：分子式 C22H30O、分子量 310.5。
| CAS号 | 54024-22-5 |
|---|---|
| 分子式 | C22H30O |
| 分子量 | 310.5 |
| 熔点 | 109-110ºC |
| 沸点 | 428ºC |
| LogP | 5.65 |
| 应用领域 | Uses: MEDICATION、Use (kg、approx.) in Germany (2009): >25、Use (kg) in USA (2002): 14、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Consumption (g per capita) in the USA (2002): 5.03e-05、Calculated removal (%): 95.8、Methods of Manufacturing:、Desogestrel、is produced by adding a solution of 11、11-methylene-18-methyl-delta4-estren-17-one in tetrahydrofuran to potassium acetylide solution in tetrahydrofuran and acidified.、Impurities: Reported impurities include: 13-ethyl-16-[13-ethyl-17beta-hydroxy-11-methylene-18、19-dinor-17alpha-pregn-4-en-20-yn-16-ylidene]-11-methylene-18、19-dinor-17alpha-pregn-4-en-20-yn-17beta-ol、13-ethyl-11-methylene-18、19-dinor-5alpha、17alpha-pregn-3-en-20-yn-17-ol (desogestrel D3-isomer) and 11-methylene-19-nor-17alpha-pregn-4-en-20-yn-17-ol、13-ethyl-11-methylenegon-4-en-17-one.、Formulations、Preparations: Oral: Tablets: 0.15 mg、0.03 mg (desogestrel and ethinyl estradiol)、Apri (Barr Laboratories Inc).、Desogestrel is available commercially only in combination with ethinylestradiol in tablets.、Oral: Tablet (film coated): 75 ug Cerazette (Organon Laboratories Limited).、General Manufacturing Information: ...manufactured or formulated in Argentina、Australia、Belgium、Brazil、Canada、France、Germany、India、Mexico、the Netherlands、South Africa、Spain、Switzerland、the United Kingdom、and the United States. |
登记用途：Uses: MEDICATION、Use (kg、approx.) in Germany (2009): >25、Use (kg) in USA (2002): 14、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Consumption (g per capita) in the USA (2002): 5.03e-05、Calculated removal (%): 95.8、Methods of Manufacturing:、Desogestrel、is produced by adding a solution of 11、11-methylene-18-methyl-delta4-estren-17-one in tetrahydrofuran to potassium acetylide solution in tetrahydrofuran and acidified.、Impurities: Reported impurities include: 13-ethyl-16-[13-ethyl-17beta-hydroxy-11-methylene-18、19-dinor-17alpha-pregn-4-en-20-yn-16-ylidene]-11-methylene-18、19-dinor-17alpha-pregn-4-en-20-yn-17beta-ol、13-ethyl-11-methylene-18、19-dinor-5alpha、17alpha-pregn-3-en-20-yn-17-ol (desogestrel D3-isomer) and 11-methylene-19-nor-17alpha-pregn-4-en-20-yn-17-ol、13-ethyl-11-methylenegon-4-en-17-one.、Formulations、Preparations: Oral: Tablets: 0.15 mg、0.03 mg (desogestrel and ethinyl estradiol)、Apri (Barr Laboratories Inc).、Desogestrel is available commercially only in combination with ethinylestradiol in tablets.、Oral: Tablet (film coated): 75 ug Cerazette (Organon Laboratories Limited).、General Manufacturing Information: ...manufactured or formulated in Argentina、Australia、Belgium、Brazil、Canada、France、Germany、India、Mexico、the Netherlands、South Africa、Spain、Switzerland、the United Kingdom、and the United States.。
去氧孕烯 是一种化工化合物，登记 CAS 号为 54024-22-5，分子式 C22H30O（分子量 310.5）。
登记 CAS 号：54024-22-5
其分子式 C22H30O 由 22 个碳、30 个氢、1 个氧 组成。
别名/同义词：去氧孕烯 · Desogestrel
去氧孕烯 的 CAS 登记号为 54024-22-5。
分子式 C22H30O，分子量 310.5。
别名/同义词：去氧孕烯、Desogestrel。
登记用途：Uses: MEDICATION、Use (kg、approx.) in Germany (2009): >25、Use (kg) in USA (2002): 14、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Consumption (g per capita) in the USA (2002): 5.03e-05、Calculated removal (%): 95.8、Methods of Manufacturing:、Desogestrel、is produced by adding a solution of 11、11-methylene-18-methyl-delta4-estren-17-one in tetrahydrofuran to potassium acetylide solution in tetrahydrofuran and acidified.、Impurities: Reported impurities include: 13-ethyl-16-[13-ethyl-17beta-hydroxy-11-methylene-18、19-dinor-17alpha-pregn-4-en-20-yn-16-ylidene]-11-methylene-18、19-dinor-17alpha-pregn-4-en-20-yn-17beta-ol、13-ethyl-11-methylene-18、19-dinor-5alpha、17alpha-pregn-3-en-20-yn-17-ol (desogestrel D3-isomer) and 11-methylene-19-nor-17alpha-pregn-4-en-20-yn-17-ol、13-ethyl-11-methylenegon-4-en-17-one.、Formulations、Preparations: Oral: Tablets: 0.15 mg、0.03 mg (desogestrel and ethinyl estradiol)、Apri (Barr Laboratories Inc).、Desogestrel is available commercially only in combination with ethinylestradiol in tablets.、Oral: Tablet (film coated): 75 ug Cerazette (Organon Laboratories Limited).、General Manufacturing Information: ...manufactured or formulated in Argentina、Australia、Belgium、Brazil、Canada、France、Germany、India、Mexico、the Netherlands、South Africa、Spain、Switzerland、the United Kingdom、and the United States.。
去氧孕烯（CAS 54024-22-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 54024-22-5 |
|---|---|
| PubChem CID | 40973 |
| Molecular formula | C22H30O |
| IUPAC name | (8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol |
| UNII (FDA) | 81K9V7M3A3 |
| Molecular Weight | 310.5 |
|---|---|
| XLogP3 | 4.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 2 |
| Exact Mass | 310.229665576 |
| Monoisotopic Mass | 310.229665576 |
| Topological Polar Surface Area | 20.2 |
| Heavy Atom Count | 23 |
| Boiling Point | 428ºC |
|---|---|
| Melting Point | 109-110ºC |
| Melting Point | 109-110 °C |
| Melting Point | 109.5 °C |
| Solubility | <1 mg/ml |
| Solubility | 3.01e-03 g/L |
| LogP | 5.65 |
| Dissociation Constants | 13.04 |
DESOGESTREL; 54024-22-5; Cerazette; Desogestrelum; Org-2969; ORG 2969; 13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol; DTXSID6022898; 81K9V7M3A3; CHEBI:4453; DTXCID702898; VOLNEA COMPONENT DESOGESTREL; BEKYREE COMPONENT DESOGESTREL; ENSKYCE COMPONENT DESOGESTREL; PIMTREA COMPONENT DESOGESTREL; VIORELE COMPONENT DESOGESTREL
| Reported hazard statements | H360 (10.8%), H372 (27.7%), H400 (60%), H410 (89.2%) |
|---|
H360 (10.8%): May damage fertility or the unborn child [Danger Reproductive toxicity]
H360Fd (26.2%): May damage fertility; Suspected of damaging the unborn child [Danger Reproductive toxicity]
Desogestrel · CAS 54024-22-5 · C22H30O. UNII 81K9V7M3A3. Boiling Point: 428ºC; Melting Point: 109-110ºC; Melting Point: 109-110 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Desogestrel