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Diphenhydramine hydrochloride

CAS 147-24-0C17H21NOMW 255.35

Diphenhydramine hydrochloride (CAS 147-24-0) — formula C17H21NO, molecular weight 255.35; category pharmaceutical intermediates and APIs.

Product Description

Diphenhydramine hydrochloride (CAS 147-24-0) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C17H21NO comprises 17 C, 21 H, 1 N, 1 O atoms. Its molecular weight is about 255.35. Reported physicochemical data: melting point around 161-162, boiling point around 150-165 °C at 2.00E+00 mm Hg, LogP about 3.27. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number147-24-0
Molecular FormulaC17H21NO
Molecular Weight255.35
Melting Point161-162
Boiling Point150-165 °C at 2.00E+00 mm Hg
LogP3.27
ApplicationsAnesthetics, Local, Anti-Allergic Agents, Antiemetics, Histamine H1 Antagonists, Hypnotics and Sedatives
CategoryPharmaceutical Intermediates & APIs

Applications

Documented applications: Anesthetics, Local, Anti-Allergic Agents, Antiemetics, Histamine H1 Antagonists, Hypnotics and Sedatives.

Technical Profile

What this product is

Diphenhydramine hydrochloride is a pharmaceutical intermediate or API compound with CAS registry number 147-24-0 and molecular formula C17H21NO (molecular weight 255.35), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Identification

CAS number: 147-24-0

Its molecular formula C17H21NO comprises 17 C, 21 H, 1 N, 1 O atoms.

Also known as: Diphenhydramine hydrochloride · 盐酸苯海拉明

Category: pharmaceutical intermediates and APIs

Frequently Asked Questions

What is the CAS number of Diphenhydramine hydrochloride?

The CAS registry number of Diphenhydramine hydrochloride is 147-24-0.

What is the molecular formula and molecular weight of Diphenhydramine hydrochloride?

Molecular formula C17H21NO, molecular weight 255.35.

What other names is Diphenhydramine hydrochloride known by?

It is also registered under: Diphenhydramine hydrochloride, 盐酸苯海拉明.

What are the documented applications of Diphenhydramine hydrochloride?

Recorded applications: Anesthetics, Local, Anti-Allergic Agents, Antiemetics, Histamine H1 Antagonists, Hypnotics and Sedatives.

Which category does Diphenhydramine hydrochloride belong to?

Category: Pharmaceutical Intermediates & APIs.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Diphenhydramine hydrochloride (CAS 147-24-0), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number147-24-0
PubChem CID3100
Molecular formulaC17H21NO
IUPAC name2-benzhydryloxy-N,N-dimethylethanamine
UNII (FDA)8GTS82S83M

Computed descriptors

Molecular Weight255.35
XLogP33.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count6
Exact Mass255.162314293
Monoisotopic Mass255.162314293
Topological Polar Surface Area12.5
Heavy Atom Count19

Physicochemical values on record

Boiling Point150-165 °C at 2.00E+00 mm Hg
Boiling PointBP: 165 °C at 3 mm Hg
Boiling PointBP: 150-165 °C at 2.0 mm Hg
Melting Point161-162
Melting Point168 °C
Solubility3060
SolubilityIn water, 3.06X10+3 mg/L at 37 °C
LogP3.27
LogPlog Kow = 3.27
LogP3.4

Documented uses on record

    Anesthetics, Local; Anti-Allergic Agents; Antiemetics; Histamine H1 Antagonists; Hypnotics and SedativesUse (kg; approx.) in Germany (2009): >2500

    Synonyms and trade names

    diphenhydramine; 58-73-1; Benzhydramine; Alledryl; Probedryl; Dihidral; Antistominum; Benzhydraminum; Benzhydroamina; Diphantine; Baramine; Dermodrin; Desentol; Dibondrin; Histaxin; Benylan

    GHS hazard classification

    Reported hazard statementsH302 (100%), H315 (66.7%), H319 (66.7%)

    H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

    H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]

    What the public record says

    (2-Diphenylmethoxyethyl)Dimethylamine Hydrochloride · CAS 147-24-0 · C17H21NO. UNII 8GTS82S83M. Boiling Point: 150-165 °C at 2.00E+00 mm Hg; Boiling Point: BP: 165 °C at 3 mm Hg; Boiling Point: BP: 150-165 °C at 2.0 mm Hg.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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