卡那替尼二盐酸盐

Description

Canertinib dihydrochloride · CAS 289499-45-2 · C24H27Cl3FN5O3. UNII ICJ93X8X90.

Identification

CAS Registry Number	289499-45-2
PubChem CID	156413
Molecular formula	C24H27Cl3FN5O3
IUPAC name	N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide;dihydrochloride
UNII (FDA)	ICJ93X8X90

Computed Descriptors

Molecular Weight	558.9
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	9
Exact Mass	557.116351
Monoisotopic Mass	557.116351
Topological Polar Surface Area	88.6
Heavy Atom Count	36
Formal Charge	0
Complexity	671

GHS Hazard Classification

Reported hazard statements	H315 (100%), H319 (100%), H335 (100%)

Documented Uses

• Substances that inhibit or prevent the proliferation of NEOPLASMS.
• Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).

Synonyms

Canertinib dihydrochloride; 289499-45-2; PD-0183805; CANERTINIB HYDROCHLORIDE; ICJ93X8X90; PD183805; PD-0183805-002B; DTXSID80183143; RefChem:202005; DTXCID90105634; 663-691-3; PD-183805; Canertinib HCl; CI-1033; Canertinib 2HCl; Canertinib (dihydrochloride)

Frequently Asked Questions

What are the CAS number and molecular formula of Canertinib dihydrochloride?

CAS 289499-45-2; molecular formula C24H27Cl3FN5O3; molecular weight — g/mol.

What other names is Canertinib dihydrochloride known by?

Canertinib dihydrochloride, 289499-45-2, PD-0183805, CANERTINIB HYDROCHLORIDE, ICJ93X8X90, PD183805.

Is Canertinib dihydrochloride classified as hazardous?

Hazard statements reported: H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.