葫芦素B

Name: 葫芦素B
Brand: 济南圣和化工有限公司

CAS 6199-67-3C32H46O8MW 558.7

葫芦素B（CAS 6199-67-3）属医药中间体及原料药类产品，分子式 C32H46O8，分子量 558.7。济南圣和化工有限公司常年现货供应该产品，常规纯度按批次COA提供(不公开发布)，可按客户需求安排分装包装，欢迎邮件或来电询价。

产品概览

CAS号	6199-67-3
分子式	C32H46O8
分子量	558.7
熔点	184-186 °C
LogP	2.6
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

葫芦素B主要应用于医药中间体及原料药。具体使用工况下的添加量与规格要求，欢迎与技术团队沟通确认。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

采购提示：本产品按按订单/批次确认(不公开发布)起订发货，收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存；如需 MSDS 或运输说明，可在询价时一并索取。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

济南圣和化工有限公司位于山东济南，主营化工原料供应，精选产品 3,000+ 种，覆盖有机化学品、无机化学品、食品添加剂、医药中间体等 12 大分类。我们随货提供 COA 分析证书，一个工作日内回复报价，欢迎国内外采购方长期合作。

常见问题

葫芦素B 的 CAS 号是多少？

葫芦素B 的 CAS 号为 6199-67-3。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

葫芦素B 有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Cucurbitacin B · CAS 6199-67-3 · C32H46O8. UNII 0115W5MABF. Melting Point: 184-186 °C.

Identification

CAS Registry Number	6199-67-3
PubChem CID	5281316
Molecular formula	C32H46O8
IUPAC name	[(E,6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
UNII (FDA)	0115W5MABF

Computed Descriptors

Molecular Weight	558.7
XLogP3	2.6
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	6
Exact Mass	558.31926842
Monoisotopic Mass	558.31926842
Topological Polar Surface Area	138
Heavy Atom Count	40
Formal Charge	0

Physical & Chemical Properties

Melting Point	184-186 °C

Physical description & handling notes

Solid; [Merck Index]
CRYSTALS FROM ABSOLUTE ETHANOL
SPECIFIC OPTICAL ROTATION: +88 DEG @ 25 °C/D (ETHANOL, 1.55%)

GHS Hazard Classification

Reported hazard statements	H300 (100%)

H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]

P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)

Documented Uses

Cucurbitacins: Isolated from cucurbitaceous plants and used as vermifuges, emetics, narcotics, and antimalarials; Reported cause of livestock poisoning in South Africa; [Merck Index] Highly toxic substance in wild cucumbers; [HSDB]
ENSLIN, J SCI FOOD AGR 5, 410 (1954); ENSLIN ET AL, J SCI FOOD 8, 673 (1957); EISENHUT, NOLLER, J ORG CHEM 23, 1984 (1958); LAVIE, WILLNER, J AM CHEM SOC 80, 710 (1958). STRUCTURE: LAVIE ET AL, CHEM & IND (LONDON) 1959, 951; DE KOCK ET AL, J CHEM SOC 1963, 3828; VAN DER MERWE ET AL, J CHEM SOC 1963, 4275. STEREOCHEMISTRY: LAVIE ET AL, J ORG CHEM 28, 1790 (1963). /CUCURBITACINS B, D, & F/
EIGHT BIOLOGICALLY ACTIVE CUCURBITACINS ISOLATED FROM ROOTS OF BRYONIA ALBA, INCLUDING CUCURBITACIN B, WERE CYTOTOXIC IN TISSUE CULTURES OF KB & HELA CELLS. CUCURBITACIN B WAS EFFECTIVE ON TRANSPLANTABLE SARCOMA 180 & EHRLICH ASCITES CARCINOMA IN MICE.
IN RATS WITH IM WALKER CARCINOSARCOMA 256 & IN MICE WITH LEWIS LUNG CARCINOMA, ADMIN OF CUCURBITACIN B 0.8-1.6 MG/KG INHIBITED TUMOR DEVELOPMENT BUT THE LOW MARGIN BETWEEN ACTIVE & TOXIC DOSES RENDERED THE MATERIAL UNPROMISING AS A THERAPEUTIC AGENT.

Synonyms

Cucurbitacin B; 6199-67-3; Amarine; Datisca principle B; Cucurbitacine B; (+)-Cucurbitacin B; Datiscn Principle B; 1,2-Dihydro-alpha-elaterin; NSC-49451; NSC-144154; 0115W5MABF; CHEBI:3941; DTXSID501316196; 25-(Acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-trione; RefChem:128713; DTXCID401746059

Frequently Asked Questions

What are the CAS number and molecular formula of Cucurbitacin B?

CAS 6199-67-3; molecular formula C32H46O8; molecular weight — g/mol.

What other names is Cucurbitacin B known by?

Cucurbitacin B, 6199-67-3, Amarine, Datisca principle B, Cucurbitacine B, (+)-Cucurbitacin B.

Is Cucurbitacin B classified as hazardous?

Hazard statements reported: H300.

What are the key physical properties of Cucurbitacin B?

Melting Point: 184-186 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.