盐酸西咪替丁

Description

Cimetidine hydrochloride · CAS 70059-30-2 · C10H17ClN6S. UNII WF10491673.

Identification

CAS Registry Number	70059-30-2
PubChem CID	50963
Molecular formula	C10H17ClN6S
IUPAC name	1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine;hydrochloride
UNII (FDA)	WF10491673

Computed Descriptors

Molecular Weight	288.80
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	288.0923934
Monoisotopic Mass	288.0923934
Topological Polar Surface Area	114
Heavy Atom Count	18
Formal Charge	0
Complexity	296

GHS Hazard Classification

Reported hazard statements	H315 (50%), H317 (50%), H319 (50%), H334 (50%), H335 (50%)

Documented Uses

• For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
• Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
• Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
• Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP1A2.
• Histamine H2 Receptor Antagonists [MoA]; Histamine-2 Receptor Antagonist [EPC]
• Hepatic Route of Elimination: The principal route of excretion of cimetidine is the urine. Half Life: 2 hours

Synonyms

Cimetidine hydrochloride; 70059-30-2; Cimetidine Hcl; WF10491673; DTXSID10990302; 2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine monohydrochloride; Guanidine, N''-cyano-N-methyl-N'-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)-, monohydrochloride; Tagamet hydrochloride in sodium chloride 0.9% in plastic container; Cimetidine hydrochloride in sodium chloride 0.9% in plastic container; CHEBI:50362; 2-Cyano-1-methyl-3-[2-[[(5-methylimidazol-4-yl)methyl]thio]ethyl]guanidine monohydrochloride; RefChem:54828; DTXCID201417406; Cimetidine Hydrochloride Oral Solution; 274-297-2; 71989-90-7

Frequently Asked Questions

What are the CAS number and molecular formula of Cimetidine hydrochloride?

CAS 70059-30-2; molecular formula C10H17ClN6S; molecular weight — g/mol.

What other names is Cimetidine hydrochloride known by?

Cimetidine hydrochloride, 70059-30-2, Cimetidine Hcl, WF10491673, DTXSID10990302, 2-Cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine monohydrochloride.

Is Cimetidine hydrochloride classified as hazardous?

Hazard statements reported: H315, H317, H319, H334, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.