CYAZOFAMID

Description

CYAZOFAMID · CAS 120116-88-3 · C13H13ClN4O2S. UNII QJC4S2YQ4B. Melting Point: 152.7 °C; Density: 1.446 at 20 °C; Vapor Pressure: 1.3X10-2 mPa /9.75X10-8 mm Hg/ at 35 °C.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Ivory odorless solid; [Merck Index]
• Ivory powder
• Odorless
• Solvent solubility (all in g/100 mL, 21.2 °C): hexane, 0.003; methanol, 0.174, acetonitrile, 3.095, dichloroethane, 10.212; toluene, 0.600, ethyl acetate, 1.649; acetone, 4.564, octanol, 0.004
• In water, 0.107 at pH 7; 0.121 at pH 5; 0.109 at pH 9 (all in mg/L at 20 °C)
• No pKa evident in pH range 2-12

GHS Hazard Classification

Documented Uses

• Used as agricultural fungicide; [Merck Index] Used to control blight on tomatoes and potatoes and downy mildew on cucurbit vegetables; [Reference #1]
• For control of diseases caused by oomycete fungi. ... controls early and late blight on tomatoes and potatoes and downy mildew on cucurbit vegetables (crop group 9).
• For control of Oomycete and Plasmodiophora diseases, such as potato and tomato late blight (Phytophthora infestans) and downy mildews (e.g. Pseudoperonospora cubensis of cucumber).
• Preparation: R. Nasu et al., AU 8812883; eidem, US 4995898 (1988, 1991 both to Ishihara Sangyo Kaisha)
• Cyazofamid has limited systemic activity so it is used as a protectant fungicide applied by ground or aerial spray.
• Both the urine and feces were major routes of excretion /in rats/ at the low dose /0.5 mg/kg/ with most of the urinary radioactivity being a metabolite named CCBA (4-(4-chloro-2-cyanoimidazol-5-yl)benzoic acid). ... Irrespective of the dosing regimen, most of the recovered fecal radioactivity was unchanged parent compound; the major fecal metabolites were CCBA and 4-chloro-5-p-tolylimidazole-2-carbonitrile (CCIM) each of which being less than 5% of the administered dose.

Synonyms

Cyazofamid; 120116-88-3; Ranman; 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide; 4-chloro-2-cyano-N,N-dimethyl-5-p-tolylimidazole-1-sulfonamide; DTXSID9034492; QJC4S2YQ4B; IKF-916; DTXCID7014492; CHEBI:81841; RefChem:129160; 601-671-8; Cyazofamid [ISO]; 4-Chloro-2-cyano-N,N-dimethyl-5-(p-tolyl)-1H-imidazole-1-sulfonamide; 1H-Imidazole-1-sulfonamide, 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-; MFCD04112761

Frequently Asked Questions

What are the CAS number and molecular formula of CYAZOFAMID?

CAS 120116-88-3; molecular formula C13H13ClN4O2S; molecular weight — g/mol.

What other names is CYAZOFAMID known by?

Cyazofamid, 120116-88-3, Ranman, 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide, 4-chloro-2-cyano-N,N-dimethyl-5-p-tolylimidazole-1-sulfonamide, DTXSID9034492.

Is CYAZOFAMID classified as hazardous?

Hazard statements reported: H400, H410.

What are the key physical properties of CYAZOFAMID?

Melting Point: 152.7 °C; Density: 1.446 at 20 °C; Vapor Pressure: 1.3X10-2 mPa /9.75X10-8 mm Hg/ at 35 °C; LogP: log Kow = 3.2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.