塞瑞替尼

Name: 塞瑞替尼
Brand: 济南圣和化工有限公司

CAS 1032900-25-6C28H36ClN5O3SMW 558.1

本页收录塞瑞替尼，CAS 登记号为 1032900-25-6，分子式 C28H36ClN5O3S，分子量 558.1，归类于医药中间体及原料药。作为主营产品之一，济南圣和化工有限公司可提供从公斤级到吨级的稳定供货，随货附 COA 与质检资料。

产品概览

CAS号	1032900-25-6
分子式	C28H36ClN5O3S
分子量	558.1
LogP	6.4
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

塞瑞替尼在医药中间体及原料药领域使用广泛。采购前请确认纯度等级与包装形式，以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供应说明：塞瑞替尼常规包装为按订单/批次确认(不公开发布)，储存时应密封置于阴凉干燥处，避免与氧化剂混放。济南圣和化工有限公司支持国内物流发货，大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

作为化工原料供应服务商，济南圣和化工有限公司长期服务于化工贸易、食品添加、医药中间体、日化原料等行业的采购需求。除塞瑞替尼外，您还可以在站内按 CAS 号或产品分类检索更多品类，获取规格与报价。

常见问题

塞瑞替尼的 CAS 号是多少？

塞瑞替尼的 CAS 号为 1032900-25-6。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

塞瑞替尼有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Ceritinib · CAS 1032900-25-6 · C28H36ClN5O3S. UNII K418KG2GET.

Identification

CAS Registry Number	1032900-25-6
PubChem CID	57379345
Molecular formula	C28H36ClN5O3S
IUPAC name	5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine
UNII (FDA)	K418KG2GET

Computed Descriptors

Molecular Weight	558.1
XLogP3	6.4
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	9
Exact Mass	557.2227389
Monoisotopic Mass	557.2227389
Topological Polar Surface Area	114
Heavy Atom Count	38
Formal Charge	0

Physical description & handling notes

9.7 and 4.1

GHS Hazard Classification

Reported hazard statements	H302 (33.3%), H360 (16.7%), H372 (66.7%), H400 (16.7%), H410 (66.7%)

H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]

H360 (16.7%): May damage fertility or the unborn child [Danger Reproductive toxicity]

Documented Uses

Ceritinib is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC). Ceritinib is associated with a moderate rate of serum aminotransferase elevations during therapy and rare instances of clinically apparent acute liver injury.
Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors; Signal Transduction Inhibitors; Tyrosine Kinase Inhibitors
Ceritinib is approved to treat:
• Non-small cell lung cancer that is ALK positive and has metastasized (spread to other parts of the body). It is used in adults.
Ceritinib is also being studied in the treatment of other types of cancer.
Avoid grapefruit products. Grapefruit inhibits the CYP3A metabolism of ceritinib, which may increase its serum concentration.

Synonyms

ceritinib; 1032900-25-6; LDK378; ZYKADIA; LDK-378; NVP-LDK378-NX; LDK 378; K418KG2GET; ceritinibum; NVP-LDK-378-NX; CHEBI:78432; DTXSID10725373; RefChem:57924; DTXCID50676118; L01XE28; 811-457-8

Frequently Asked Questions

What are the CAS number and molecular formula of Ceritinib?

CAS 1032900-25-6; molecular formula C28H36ClN5O3S; molecular weight — g/mol.

What other names is Ceritinib known by?

ceritinib, 1032900-25-6, LDK378, ZYKADIA, LDK-378, NVP-LDK378-NX.

Is Ceritinib classified as hazardous?

Hazard statements reported: H302, H360, H372, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.