盐酸卡替洛尔

Description

carteolol hydrochloride · CAS 51781-21-6 · C16H25ClN2O3. UNII 4797W6I0T4.

Identification

CAS Registry Number	51781-21-6
PubChem CID	40127
Molecular formula	C16H25ClN2O3
IUPAC name	5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-quinolin-2-one;hydrochloride
UNII (FDA)	4797W6I0T4

Computed Descriptors

Molecular Weight	328.83
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	328.1553704
Monoisotopic Mass	328.1553704
Topological Polar Surface Area	70.6
Heavy Atom Count	22
Formal Charge	0
Complexity	354

Regulatory Status

GHS notification summary	16.7% (1 / 6)

GHS Hazard Classification

GHS notification summary	16.7% (1 / 6)
Reported hazard statements	H302 (83.3%), H319 (33.3%), H351 (16.7%), H361 (50%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Adrenergic Beta-Antagonists; Antiglaucoma Agents
• Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
• Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.
• Adrenergic beta-Antagonists [MoA]; beta-Adrenergic Blocker [EPC]

Synonyms

carteolol hydrochloride; 51781-21-6; Carteolol HCl; Cartrol; Ocupress; Abbott-43326; OPC-1085; Teoptic; DTXSID4045478; NSC-300906; 4797W6I0T4; DTXCID2025478; 5-(2-Hydroxy-3-tert-butylamino)propoxy-3,4-dihydrocarbostyril hydrochloride; 5-(3-(tert-Butylamino)-2-hydroxypropoxy)-3,4-dihydrocarbostyril monohydrochloride; NSC300906; 5-(3-((1,1-Dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-2(1H)-quinolinone hydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of carteolol hydrochloride?

CAS 51781-21-6; molecular formula C16H25ClN2O3; molecular weight — g/mol.

What other names is carteolol hydrochloride known by?

carteolol hydrochloride, 51781-21-6, Carteolol HCl, Cartrol, Ocupress, Abbott-43326.

Is carteolol hydrochloride classified as hazardous?

16.7% of GHS notifications report no hazard classification (1 of 6).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.