Carbimazole

Description

Carbimazole · CAS 22232-54-8 · C7H10N2O2S. UNII 8KQ660G60G. Melting Point: 123.5; Melting Point: 123.5 °C; Solubility: 3.14e+00 g/L.

Identification

CAS Registry Number	22232-54-8
PubChem CID	31072
Molecular formula	C7H10N2O2S
IUPAC name	ethyl 3-methyl-2-sulfanylideneimidazole-1-carboxylate
UNII (FDA)	8KQ660G60G

Computed Descriptors

Molecular Weight	186.23
XLogP3	0.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	186.04629874
Monoisotopic Mass	186.04629874
Topological Polar Surface Area	64.9
Heavy Atom Count	12
Formal Charge	0

Physical & Chemical Properties

Melting Point	123.5
Melting Point	123.5 °C
Solubility	3.14e+00 g/L
LogP	0.4

Physical description & handling notes

• Solid
• 148.0 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9022736]
• 143.69 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 143.43 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 128.01 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 134.47 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (18.6%), H317 (14%), H319 (18.6%), H360 (81.4%), H373 (81.4%), H400 (81.4%), H410 (81.4%), H362

Documented Uses

• Use (kg; approx.) in Germany (2009): >250
• Consumption (g per capita; approx.) in Germany (2009): 0.00305
• Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
• For the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.
• Breast Feeding; Lactation; Milk, Human; Antithyroid Agents; Thionamides
• Thyroid hormones and antithyroid medicines

Synonyms

Carbimazole; 22232-54-8; Athyromazole; Carbimazol; Carbethoxymethimazole; Carbinazole; Carbimazolum; Ethyl 3-methyl-2-thioimidazoline-1-carboxylate; Carbimazol henning; DTXSID9022736; NSC-758966; CHEBI:617099; 8KQ660G60G; ethyl 3-methyl-2-sulfanylidene-2,3-dihydro-1H-imidazole-1-carboxylate; 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo, ethyl ester; DTXCID902736

Frequently Asked Questions

What are the CAS number and molecular formula of Carbimazole?

CAS 22232-54-8; molecular formula C7H10N2O2S; molecular weight — g/mol.

What other names is Carbimazole known by?

Carbimazole, 22232-54-8, Athyromazole, Carbimazol, Carbethoxymethimazole, Carbinazole.

Is Carbimazole classified as hazardous?

Hazard statements reported: H302, H317, H319, H360, H373.

What are the key physical properties of Carbimazole?

Melting Point: 123.5; Melting Point: 123.5 °C; Solubility: 3.14e+00 g/L; LogP: 0.4.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.