烟酸铬

Description

Chromium nicotinate · CAS 64452-96-6 · C18H12CrN3O6. UNII A150AY412V.

Identification

CAS Registry Number	64452-96-6
PubChem CID	9909912
Molecular formula	C18H12CrN3O6
IUPAC name	chromium(3+);tris(pyridine-3-carboxylate)
UNII (FDA)	A150AY412V

Computed Descriptors

Molecular Weight	418.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	0
Exact Mass	418.013115
Monoisotopic Mass	418.013115
Topological Polar Surface Area	159
Heavy Atom Count	28
Formal Charge	0
Complexity	108

Documented Uses

• Indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN), to maintain chromium serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.
• Administer vitamin supplements. Foods or supplements containing niacin (Vitamin B3) may improve the absorption of chromium.
• Take with foods containing vitamin C. Foods rich in vitamin C increase the absorption of chromium.
• Chromium compounds are both absorbed by the lung and the gastrointestinal tract. Oral absorption of chromium compounds in humans can range between 0.5% and 10%, with the hexavalent (VI) chromium more easily absorbed than the trivalent (III) form. Absorption of chromium from the intestinal tract is low, ranging from less than 0.4% to 2.5% of the amount consumed. Vitamin C and the vitamin B niacin is reported to enhance chromium absorption. Most hexavalent Cr (VI) undergoes partial intragastric reduction to Cr (III)
• Absorbed chromium is excreted mainly in the urine, accounting for 80% of total excretion of chromium; small amounts are lost in hair, perspiration and bile. Chromium is excreted primarily in the urine by glomerular filtration or bound to a low molecular-weight organic transporter.
• Absorbed chromium is distributed to all tissues of the body and its distribution in the body depends on the species, age, and chemical form. Circulating Cr (III) following oral or parenteral administration of different compounds can be taken up by tissues and accumulates in the liver, kidney, spleen, soft tissue, and bone.

Synonyms

Chromium nicotinate; Chromium(III) nicotinate; 64452-96-6; DTXSID8040561; 3-Pyridinecarboxylic acid, chromium(3+) salt (3:1); A150AY412V; Cr-NAC; RefChem:576919; DTXCID6020561; chromium niacinate; Cr-nicotinic acid; chromium(3+);pyridine-3-carboxylate; chromium: pyridine-3-carboxylate; chromium trinicotinate; chromium(3+) tripyridine-3-carboxylate; CHROMIUM TRI-NICOTINATE

Frequently Asked Questions

What are the CAS number and molecular formula of Chromium nicotinate?

CAS 64452-96-6; molecular formula C18H12CrN3O6; molecular weight — g/mol.

What other names is Chromium nicotinate known by?

Chromium nicotinate, Chromium(III) nicotinate, 64452-96-6, DTXSID8040561, 3-Pyridinecarboxylic acid, chromium(3+) salt (3:1), A150AY412V.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.