Cetirizine (CAS 83881-51-0) — formula C21H25ClN2O3, molecular weight 388.9; category pharmaceutical intermediates and APIs.
Cetirizine (CAS 83881-51-0) is a pharmaceutical intermediates and APIs. Its molecular formula C21H25ClN2O3 comprises 21 C, 25 H, 1 Cl, 2 N, 3 O atoms. Its molecular weight is about 388.9. Reported physicochemical data: melting point around 110-115°C, boiling point around 542.1, LogP about 2.8. Pharmaceutical intermediates and APIs are critical building blocks for drug synthesis, with strict requirements on purity, impurities and process consistency. Used in API synthesis, formulation and pre-clinical research; supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 83881-51-0 |
|---|---|
| Molecular Formula | C21H25ClN2O3 |
| Molecular Weight | 388.9 |
| Melting Point | 110-115°C |
| Boiling Point | 542.1 |
| LogP | 2.8 |
| Applications | A second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma, THERAP CAT: Antihistaminic, Use (kg) in Switzerland (2009): >100, Use (kg |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: A second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma, THERAP CAT: Antihistaminic, Use (kg) in Switzerland (2009): >100, Use (kg.
Cetirizine is a pharmaceutical intermediate or API compound with CAS registry number 83881-51-0 and molecular formula C21H25ClN2O3 (molecular weight 388.9), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 83881-51-0
Its molecular formula C21H25ClN2O3 comprises 21 C, 25 H, 1 Cl, 2 N, 3 O atoms.
Also known as: Cetirizine · 西替利嗪
Category: pharmaceutical intermediates and APIs
The CAS registry number of Cetirizine is 83881-51-0.
Molecular formula C21H25ClN2O3, molecular weight 388.9.
It is also registered under: Cetirizine, 西替利嗪.
Recorded applications: A second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma, THERAP CAT: Antihistaminic, Use (kg) in Switzerland (2009): >100, Use (kg.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Cetirizine (CAS 83881-51-0), compiled from public chemistry databases.
| CAS Registry Number | 83881-51-0 |
|---|---|
| PubChem CID | 2678 |
| Molecular formula | C21H25ClN2O3 |
| IUPAC name | 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid |
| UNII (FDA) | YO7261ME24 |
| Molecular Weight | 388.9 |
|---|---|
| XLogP3 | 1.7 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 8 |
| Exact Mass | 388.1553704 |
| Monoisotopic Mass | 388.1553704 |
| Topological Polar Surface Area | 53 |
| Heavy Atom Count | 27 |
| Boiling Point | 542.1 |
|---|---|
| Melting Point | 110-115°C |
| Melting Point | 110-115 °C |
| Melting Point | 112.5 °C |
| Solubility | 101 |
| LogP | 2.8 |
| LogP | log Kow = 1.70 |
cetirizine; 83881-51-0; Cetirizina; Virlix; Ziptek; Cetryn; Setir; Cetirizinum; Cetirizin; Hitrizin Film Tablet; Cetiderm; Reactine; 2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid; 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid; 2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid; YO7261ME24
| Reported hazard statements | H302 (100%) |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Cetirizine · CAS 83881-51-0 · C21H25ClN2O3. UNII YO7261ME24. Boiling Point: 542.1; Melting Point: 110-115°C; Melting Point: 110-115 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 西替利嗪