bretylium tosylate

Description

bretylium tosylate · CAS 61-75-6 · C18H24BrNO3S. UNII 78ZP3YR353.

Identification

Computed Descriptors

Physical description & handling notes

• >62.2 [ug/mL] (The mean of the results at pH 7.4)
• 140.6 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Documented Uses

• Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Drugs that bind to but do not activate ADRENERGIC RECEPTORS. Adrenergic antagonists block the actions of the endogenous adrenergic transmitters EPINEPHRINE and NOREPINEPHRINE.
• C01B - Antiarrhythmics, class i and iii
• C01BD - Antiarrhythmics, class iii
• QC01B - Antiarrythmics, class i and iii

Synonyms

Bretylium tosylate; 61-75-6; Bretylol; Bretylium tosilate; Darentin; Tosilato de bretilio; Tosilate de bretylium; Bretylii tosilas; ASL-603; (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate; Bretilio tosilato; DTXSID1022685; Bretylium Tosylate In Dextrose 5%; NSC-62164; 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-methylbenzenesulfonate; Dimethylethyl-o-bromobenzylammonium-p-toluenesulphonate

Frequently Asked Questions

What are the CAS number and molecular formula of bretylium tosylate?

CAS 61-75-6; molecular formula C18H24BrNO3S; molecular weight — g/mol.

What other names is bretylium tosylate known by?

Bretylium tosylate, 61-75-6, Bretylol, Bretylium tosilate, Darentin, Tosilato de bretilio.

Is bretylium tosylate classified as hazardous?

Hazard statements reported: H302, H312, H332.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.