倍他司汀（碱和/或未指定的盐）

Description

Betahistine (base and/or unspecified salts) · CAS 5638-76-6 · C8H12N2. UNII X32KK4201D. Boiling Point: 210.9±15.0 °C; Melting Point: 150-144; LogP: 0.1.

Identification

CAS Registry Number	5638-76-6
PubChem CID	2366
Molecular formula	C8H12N2
IUPAC name	N-methyl-2-pyridin-2-ylethanamine
UNII (FDA)	X32KK4201D

Computed Descriptors

Molecular Weight	136.19
XLogP3	0.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Exact Mass	136.100048391
Monoisotopic Mass	136.100048391
Topological Polar Surface Area	24.9
Heavy Atom Count	10
Formal Charge	0

Physical & Chemical Properties

Boiling Point	210.9±15.0 °C
Melting Point	150-144
LogP	0.1
LogP	0.68
Dissociation Constants	3.5, 9.7

Physical description & handling notes

• Solid
• 128.98 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 132.35 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 125.07 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• Through its actions on the histamine receptors, betahistine provides relief from vertigo associated with Ménière's disease.

GHS Hazard Classification

Reported hazard statements	H315 (100%), H319 (100%), H335 (97.9%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >1000
• Consumption (g per capita; approx.) in Germany (2009): 0.0122
• 2-Pyridineethanamine, N-methyl-: INACTIVE
• Investigated for use/treatment in adverse effects (drug), hyperlipidemia, and obesity.
• Betahistine is indicated for the reduction of recurrent vertigo episodes associated with Ménière's disease in patients 18 years old and above.
• Take with food. This may reduce or prevent gastrointestinal upset.

Synonyms

betahistine; 5638-76-6; N-Methyl-2-pyridineethanamine; Vasomotal; 2-Pyridineethanamine, N-methyl-; Betahistina; 2-[2-(Methylamino)ethyl]pyridine; N-methyl-2-pyridin-2-ylethanamine; Betahistinum; methyl[2-(pyridin-2-yl)ethyl]amine; Betaistina; 2-(2-(Methylamino)ethyl)pyridine; Vestibo; (2-(2-Pyridyl)ethyl)methylamine; [2-(2-Pyridyl)ethyl]methylamine; 2-(beta-Methylaminoethyl)pyridine

Frequently Asked Questions

What are the CAS number and molecular formula of Betahistine (base and/or unspecified salts)?

CAS 5638-76-6; molecular formula C8H12N2; molecular weight — g/mol.

What other names is Betahistine (base and/or unspecified salts) known by?

betahistine, 5638-76-6, N-Methyl-2-pyridineethanamine, Vasomotal, 2-Pyridineethanamine, N-methyl-, Betahistina.

Is Betahistine (base and/or unspecified salts) classified as hazardous?

Hazard statements reported: H315, H319, H335.

What are the key physical properties of Betahistine (base and/or unspecified salts)?

Boiling Point: 210.9±15.0 °C; Melting Point: 150-144; LogP: 0.1; LogP: 0.68.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.