布加替尼

Name: 布加替尼
Brand: 济南圣和化工有限公司

CAS 1197953-54-0C29H39ClN7O2PMW 584.1

布加替尼（CAS 1197953-54-0）属医药中间体及原料药类产品，分子式 C29H39ClN7O2P，分子量 584.1。济南圣和化工有限公司常年现货供应该产品，常规纯度按批次COA提供(不公开发布)，可按客户需求安排分装包装，欢迎邮件或来电询价。

产品概览

CAS号	1197953-54-0
分子式	C29H39ClN7O2P
分子量	584.1
LogP	5.17
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

布加替尼在医药中间体及原料药领域使用广泛。采购前请确认纯度等级与包装形式，以批次 COA 为验收依据。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

采购提示：本产品按按订单/批次确认(不公开发布)起订发货，收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存；如需 MSDS 或运输说明，可在询价时一并索取。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

济南圣和化工有限公司位于山东济南，主营化工原料供应，精选产品 3,000+ 种，覆盖有机化学品、无机化学品、食品添加剂、医药中间体等 12 大分类。我们随货提供 COA 分析证书，一个工作日内回复报价，欢迎国内外采购方长期合作。

常见问题

布加替尼的 CAS 号是多少？

布加替尼的 CAS 号为 1197953-54-0。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

布加替尼有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Brigatinib · CAS 1197953-54-0 · C29H39ClN7O2P. UNII HYW8DB273J. LogP: 5.17.

Identification

CAS Registry Number	1197953-54-0
PubChem CID	68165256
Molecular formula	C29H39ClN7O2P
IUPAC name	5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidine-2,4-diamine
UNII (FDA)	HYW8DB273J

Computed Descriptors

Molecular Weight	584.1
XLogP3	4.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	8
Exact Mass	583.2591382
Monoisotopic Mass	583.2591382
Topological Polar Surface Area	85.9
Heavy Atom Count	40
Formal Charge	0

Physical & Chemical Properties

LogP	5.17

Physical description & handling notes

Insoluble

GHS Hazard Classification

Reported hazard statements	H301 (100%), H361 (100%), H372 (100%), H410 (100%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

Brigatinib is a tyrosine kinase receptor inhibitor and antineoplastic agent used in the therapy of selected forms of advanced non-small cell lung cancer. Brigatinib is associated with a moderate rate of transient elevations in serum aminotransferase levels during therapy but has yet to be linked to instances of clinically apparent acute liver injury.
Breast Feeding; Lactation; Antineoplastic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors; Signal Transduction Inhibitors; Tyrosine Kinase Inhibitors;
Brigatinib is approved to treat:
• Non-small cell lung cancer that is ALK positive and has metastasized (spread to other parts of the body). It is used in adults.
Brigatinib is also being studied in the treatment of other types of cancer.
Avoid grapefruit products. Grapefruit inhibits CYP3A metabolism, which may increase the serum concentration of brigatinib.

Synonyms

Brigatinib; 1197953-54-0; ALUNBRIG; AP-26113; HYW8DB273J; DTXSID501027929; brigatinibum; RefChem:56949; L01XE43; DTXCID501513495; AP 26113; Brigatinib [USAN]; Brigatinib (AP-26113); MFCD29472221; Brigatinib (AP26113); NCGC00483924-01

Frequently Asked Questions

What are the CAS number and molecular formula of Brigatinib?

CAS 1197953-54-0; molecular formula C29H39ClN7O2P; molecular weight — g/mol.

What other names is Brigatinib known by?

Brigatinib, 1197953-54-0, ALUNBRIG, AP-26113, HYW8DB273J, DTXSID501027929.

Is Brigatinib classified as hazardous?

Hazard statements reported: H301, H361, H372, H410.

What are the key physical properties of Brigatinib?

LogP: 5.17.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.