布替萘芬

Description

Butenafine · CAS 101828-21-1 · C23H27N. UNII 91Y494NL0X. Solubility: 7.56e-05 g/L; LogP: 6.6.

Identification

CAS Registry Number	101828-21-1
PubChem CID	2484
Molecular formula	C23H27N
IUPAC name	1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine
UNII (FDA)	91Y494NL0X

Computed Descriptors

Molecular Weight	317.5
XLogP3	6.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	5
Exact Mass	317.214349865
Monoisotopic Mass	317.214349865
Topological Polar Surface Area	3.2
Heavy Atom Count	24
Formal Charge	0

Physical & Chemical Properties

Solubility	7.56e-05 g/L
LogP	6.6

Physical description & handling notes

• Solid
• Slightly soluble (HCl salt)

Documented Uses

• For the topical treatment of the following dermatologic infections: tinea (pityriasis) versicolor due to M. furfur, interdigital tinea pedis (athlete’s foot), tinea corporis (ringworm) and tinea cruris (jock itch) due to E. floccosum, T. mentagrophytes, T. rubrum, and T. tonsurans.
• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antifungal Agents
• Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
• Established Pharmacologic Class [EPC] - Benzylamine Antifungal
• Chemical Structure [CS] - Benzylamines
• Butenafine is a Benzylamine Antifungal.

Synonyms

butenafine; 101828-21-1; Butenafina; Butenafinum; N-(p-tert-Butylbenzyl)-N-methyl-1-naphthalenemethylamine; DTXSID7040657; 91Y494NL0X; 4-tert-butylbenzyl(methyl)(1-naphthalenemethyl)amine; CHEBI:3238; DTXCID5020657; (4-tert-Butyl-benzyl)-methyl-naphthalen-1-ylmethyl-amine; (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine; ((4-tert-butylphenyl)methyl)(methyl)(naphthalen-1-ylmethyl)amine; [(4-tert-butylphenyl)methyl](methyl)(naphthalen-1-ylmethyl)amine; RefChem:54581; D01AE23

Frequently Asked Questions

What are the CAS number and molecular formula of Butenafine?

CAS 101828-21-1; molecular formula C23H27N; molecular weight — g/mol.

What other names is Butenafine known by?

butenafine, 101828-21-1, Butenafina, Butenafinum, N-(p-tert-Butylbenzyl)-N-methyl-1-naphthalenemethylamine, DTXSID7040657.

What are the key physical properties of Butenafine?

Solubility: 7.56e-05 g/L; LogP: 6.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.