巴瑞克替尼

Name: 巴瑞克替尼
Brand: 济南圣和化工有限公司

CAS 1187594-09-7C16H17N7O2SMW 371.4

巴瑞克替尼（CAS 1187594-09-7）属医药中间体及原料药类产品，分子式 C16H17N7O2S，分子量 371.4。济南圣和化工有限公司常年现货供应该产品，常规纯度按批次COA提供(不公开发布)，可按客户需求安排分装包装，欢迎邮件或来电询价。

产品概览

CAS号	1187594-09-7
分子式	C16H17N7O2S
分子量	371.4
沸点	707.2
LogP	-0.5
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

该产品的下游应用集中在医药中间体及原料药。不同客户工艺差异较大，我们支持按需提供样品与小批量试用。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供货能力：巴瑞克替尼备有现货，包装形式为按订单/批次确认(不公开发布)。我们支持对公转账并开具增值税发票，山东省内可安排快速配送，省外按物流时效发货，具体请联系 info@591daili.com。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择济南圣和化工有限公司的理由：产品信息透明（含 CAS、分子式、理化参数）、报价响应快（一个工作日内）、单证齐全（COA/MSS/质检资料按需提供）、支持批量与长期协议供货。如需巴瑞克替尼以外的配套原料，也欢迎一并列出需求清单。

常见问题

巴瑞克替尼的 CAS 号是多少？

巴瑞克替尼的 CAS 号为 1187594-09-7。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

巴瑞克替尼有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Baricitinib · CAS 1187594-09-7 · C16H17N7O2S. UNII ISP4442I3Y. Boiling Point: 707.2.

Identification

CAS Registry Number	1187594-09-7
PubChem CID	44205240
Molecular formula	C16H17N7O2S
IUPAC name	2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile
UNII (FDA)	ISP4442I3Y

Computed Descriptors

Molecular Weight	371.4
XLogP3	-0.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	5
Exact Mass	371.11644398
Monoisotopic Mass	371.11644398
Topological Polar Surface Area	129
Heavy Atom Count	26
Formal Charge	0

Physical & Chemical Properties

Boiling Point	707.2

GHS Hazard Classification

Reported hazard statements	H302 (50%), H335 (16.7%), H360 (66.7%), H372 (16.7%), H373 (66.7%), H411 (66.7%)

H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]

H335 (16.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

Documented Uses

Baricitinib is a disease-modifying antirheumatic drug (DMARD) indicated for rheumatoid arthritis when conventional DMARDs prove inadequate.
Baricitinib is an orally available small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, severe alopecia areata, and, in combination with remdesivir, severe COVID-19 in hospitalized patients requiring supplementary oxygen. Baricitinib is associated with transient and usually mild elevations in serum aminotransferase levels during therapy but has yet to be linked to cases of clinically apparent acute liver injury.
Breast Feeding; Lactation; Milk, Human; Antirheumatic Agents; Enzyme Inhibitors; Janus Kinase Inhibitors; JAK Inhibitors; Signal Transduction Inhibitors; Protein Kinase Inhibitors
Baricitinib (Class: Other Substances, Added Date: 03-2022)
Take with or without food. A high-fat meal can decrease the mean AUC and Cmax of baricitinib and delay Tmax, but not to a clinically singificant extent.
Established Pharmacologic Class [EPC] - Janus Kinase Inhibitor

Synonyms

Baricitinib; 1187594-09-7; olumiant; LY3009104; INCB028050; INCB 028050; INCB-028050; 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile; LY-3009104; LY 3009104; ISP4442I3Y; DTXCID5074719; CHEBI:95341; DTXSID30152228; L04AA37; 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-(4-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-1H-pyrazol-1-yl)-

Frequently Asked Questions

What are the CAS number and molecular formula of Baricitinib?

CAS 1187594-09-7; molecular formula C16H17N7O2S; molecular weight — g/mol.

What other names is Baricitinib known by?

Baricitinib, 1187594-09-7, olumiant, LY3009104, INCB028050, INCB 028050.

Is Baricitinib classified as hazardous?

Hazard statements reported: H302, H335, H360, H372, H373.

What are the key physical properties of Baricitinib?

Boiling Point: 707.2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.