盐酸阿普洛尔

Description

alprenolol hydrochloride · CAS 13707-88-5 · C15H24ClNO2. UNII 2502C2OIRK.

Identification

CAS Registry Number	13707-88-5
PubChem CID	66368
Molecular formula	C15H24ClNO2
IUPAC name	1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol;hydrochloride
UNII (FDA)	2502C2OIRK

Computed Descriptors

Molecular Weight	285.81
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	8
Exact Mass	285.1495567
Monoisotopic Mass	285.1495567
Topological Polar Surface Area	41.5
Heavy Atom Count	19
Formal Charge	0
Complexity	231

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
• Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.

Synonyms

Alprenolol hydrochloride; 13707-88-5; Alprenolol HCl; Apllobal; Gubernal; Regletin; Aptine; Dimacor; Yobir; Aptol duriles; Dl-alprenolol chloride; H 56/28; 1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol hydrochloride; 2502C2OIRK; H-56/28; 1-(2-Allylphenoxy)-3-isopropylamino-2-propanol hydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of alprenolol hydrochloride?

CAS 13707-88-5; molecular formula C15H24ClNO2; molecular weight — g/mol.

What other names is alprenolol hydrochloride known by?

Alprenolol hydrochloride, 13707-88-5, Alprenolol HCl, Apllobal, Gubernal, Regletin.

Is alprenolol hydrochloride classified as hazardous?

Hazard statements reported: H302.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.