阿帕佐尼

Description

Apazone · CAS 13539-59-8 · C16H20N4O2. UNII K2VOT966ZI. Melting Point: 187.

Identification

CAS Registry Number	13539-59-8
PubChem CID	26098
Molecular formula	C16H20N4O2
IUPAC name	5-(dimethylamino)-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione
UNII (FDA)	K2VOT966ZI

Computed Descriptors

Molecular Weight	300.36
XLogP3	4
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	300.15862589
Monoisotopic Mass	300.15862589
Topological Polar Surface Area	56.2
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

Melting Point	187

Physical description & handling notes

• 169.5 Ų [M+H]+ [CCS Type: TW; Method: Major Mix IMS/Tof Calibration Kit (Waters)]

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Anti-Inflammatory Agents, Nonsteroidal; Uricosuric Agents
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
• M01 - Antiinflammatory and antirheumatic products
• M01A - Antiinflammatory and antirheumatic products, non-steroids
• M01AX - Other antiinflammatory and antirheumatic agents, non-steroids

Synonyms

Azapropazone; APAZONE; 13539-59-8; Cinnopropazone; Azapropazona; Azapropazonum; Azapropazon; AHR-3018; Mi-85; NSC-102824; DTXSID6045408; K2VOT966ZI; 3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine; 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione; 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione; 1,2-Dihydro-3-dimethylamino-7-methyl-1,2-(propylmalonyl)-1,2,4-benzotriazine

Frequently Asked Questions

What are the CAS number and molecular formula of Apazone?

CAS 13539-59-8; molecular formula C16H20N4O2; molecular weight — g/mol.

What other names is Apazone known by?

Azapropazone, APAZONE, 13539-59-8, Cinnopropazone, Azapropazona, Azapropazonum.

What are the key physical properties of Apazone?

Melting Point: 187.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.