氨柔比星

Description

Amrubicin · CAS 110267-81-7 · C25H25NO9. UNII 93N13LB4Z2. Boiling Point: 717.8; Melting Point: 172-174; LogP: 2.64.

Identification

CAS Registry Number	110267-81-7
PubChem CID	3035016
Molecular formula	C25H25NO9
IUPAC name	(7S,9S)-9-acetyl-9-amino-7-[(2S,4S,5R)-4,5-dihydroxyoxan-2-yl]oxy-6,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
UNII (FDA)	93N13LB4Z2

Computed Descriptors

Molecular Weight	483.5
XLogP3	0.9
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	3
Exact Mass	483.15293138
Monoisotopic Mass	483.15293138
Topological Polar Surface Area	177
Heavy Atom Count	35
Formal Charge	0

Physical & Chemical Properties

Boiling Point	717.8
Melting Point	172-174
LogP	2.64

Physical description & handling notes

• not soluble in water, but soluble in DMSO

Documented Uses

• Investigated for use/treatment in lung cancer.
• Substances that inhibit or prevent the proliferation of NEOPLASMS.
• L - Antineoplastic and immunomodulating agents
• L01D - Cytotoxic antibiotics and related substances
• L01DB - Anthracyclines and related substances
• QL - Antineoplastic and immunomodulating agents

Synonyms

Amrubicin; 110267-81-7; amrubicina; amrubicine; amrubicinum; 93N13LB4Z2; CHEBI:135779; DTXSID30869526; RefChem:557927; DTXCID00817498; L01DB10; Amrubicin(SM-5887); Amrubicin [INN]; C25H25NO9; Amrubicin [USAN:INN]; UNII-93N13LB4Z2

Frequently Asked Questions

What are the CAS number and molecular formula of Amrubicin?

CAS 110267-81-7; molecular formula C25H25NO9; molecular weight — g/mol.

What other names is Amrubicin known by?

Amrubicin, 110267-81-7, amrubicina, amrubicine, amrubicinum, 93N13LB4Z2.

What are the key physical properties of Amrubicin?

Boiling Point: 717.8; Melting Point: 172-174; LogP: 2.64.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.