盐酸艾乐替尼

盐酸艾乐替尼（CAS 1256589-74-8）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

计算分子描述符

在册的理化数值

在册的记载用途

Alectinib is indicated for the treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC). It is also indicated as an adjuvant treatment in adult patients following tumor resection of ALK-positive non-small cell lung cancer.Alectinib is a tyrosine kinase receptor inhibitor and antineoplastic agent used in the therapy of selected forms of non-small cell lung cancer. Alectinib is associated with a high rate of serum aminotransferase elevations during therapy and with rare instances of clinically apparent acute liver injury.

同义词与商品名

Alectinib; 1256580-46-7; CH5424802; CH 5424802; AF-802; RO5424802; CH-5424802; AF802; 9-ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile; AF 802; LIJ4CT1Z3Y; RO-5424802; CHEBI:90936; DTXSID50154840; RG7853; 9-ETHYL-6,6-DIMETHYL-8-[4-(MORPHOLIN-4-YL)PIPERIDIN-1-YL]-11-OXO-5H,6H,11H-BENZO[B]CARBAZOLE-3-CARBONITRILE

已收录的法规名录

GHS notification summary	66.7% (2 / 3)

GHS 危害分类

GHS notification summary	66.7% (2 / 3)
Reported hazard statements	H341 (33.3%), H361 (33.3%), H373 (33.3%)

This chemical does not meet GHS hazard criteria for 66.7% (2 of 3) of all reports.

H341 (33.3%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]

公开数据库对它的描述

Alectinib hydrochloride · CAS 1256589-74-8 · C30H34N4O2. UNII LIJ4CT1Z3Y. Dissociation Constants: 7.05.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。