Axitinib (CAS 319460-85-0) — formula C22H18N4OS, molecular weight 386.5; category pharmaceutical intermediates and APIs.
Axitinib (CAS 319460-85-0) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C22H18N4OS comprises 22 C, 18 H, 4 N, 1 O, 1 S atoms. Its molecular weight is about 386.5. Reported physicochemical data: LogP about 3.8. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 319460-85-0 |
|---|---|
| Molecular Formula | C22H18N4OS |
| Molecular Weight | 386.5 |
| LogP | 3.8 |
| Category | Pharmaceutical Intermediates & APIs |
Axitinib is a pharmaceutical intermediate or API compound with CAS registry number 319460-85-0 and molecular formula C22H18N4OS (molecular weight 386.5), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 319460-85-0
Its molecular formula C22H18N4OS comprises 22 C, 18 H, 4 N, 1 O, 1 S atoms.
Also known as: Axitinib · 阿西替尼
Category: pharmaceutical intermediates and APIs
The CAS registry number of Axitinib is 319460-85-0.
Molecular formula C22H18N4OS, molecular weight 386.5.
It is also registered under: Axitinib, 阿西替尼.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Axitinib (CAS 319460-85-0), compiled from public chemistry databases.
| CAS Registry Number | 319460-85-0 |
|---|---|
| PubChem CID | 6450551 |
| Molecular formula | C22H18N4OS |
| IUPAC name | N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide |
| UNII (FDA) | C9LVQ0YUXG |
| Molecular Weight | 386.5 |
|---|---|
| XLogP3 | 4.2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 386.12013238 |
| Monoisotopic Mass | 386.12013238 |
| Topological Polar Surface Area | 96 |
| Heavy Atom Count | 28 |
| LogP | 3.8 |
|---|---|
| Dissociation Constants | 4.8 |
Axitinib; 319460-85-0; Inlyta; AG-13736; axitinibum; C9LVQ0YUXG; DTXSID3049049; AG013736; NSC-757441; N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide; N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide; DTXCID8028975; CHEBI:66910; Benzamide, N-methyl-2-((3-((E)-2-(2-pyridinyl)ethenyl)-1H-indazol-6-yl)thio)-; N-methyl-2-({3-[(1E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide; Benzamide, N-methyl-2-((3-((1E)-2-(2-pyridinyl)ethenyl)-1H-indazo)-6-yl)thio)-
| Reported hazard statements | H302 (53.4%), H341 (43.8%), H361 (43.8%), H373 (43.8%), H400 (56.2%) |
|---|
H302 (53.4%): Harmful if swallowed [Warning Acute toxicity, oral]
H341 (43.8%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]
Axitinib · CAS 319460-85-0 · C22H18N4OS. UNII C9LVQ0YUXG. LogP: 3.8; Dissociation Constants: 4.8.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 阿西替尼