阿折地平

Name: 阿折地平
Brand: 济南圣和化工有限公司

CAS 123524-52-7C33H34N4O6MW 582.6

济南圣和化工主营供应阿折地平（CAS 123524-52-7），归类于医药中间体及原料药，分子式 C33H34N4O6，分子量 582.6。我们面向国内化工贸易与生产企业提供稳定的现货供应，报价响应快，支持对公转账并可开具增值税发票。

产品概览

CAS号	123524-52-7
分子式	C33H34N4O6
分子量	582.6
熔点	193-195
LogP	5.18
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	医药中间体及原料药
类别	医药中间体及原料药

应用领域

医药中间体及原料药

阿折地平主要应用于医药中间体及原料药。具体使用工况下的添加量与规格要求，欢迎与技术团队沟通确认。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供应说明：阿折地平常规包装为按订单/批次确认(不公开发布)，储存时应密封置于阴凉干燥处，避免与氧化剂混放。济南圣和化工有限公司支持国内物流发货，大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择济南圣和化工有限公司的理由：产品信息透明（含 CAS、分子式、理化参数）、报价响应快（一个工作日内）、单证齐全（COA/MSS/质检资料按需提供）、支持批量与长期协议供货。如需阿折地平以外的配套原料，也欢迎一并列出需求清单。

常见问题

阿折地平的 CAS 号是多少？

阿折地平的 CAS 号为 123524-52-7。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

阿折地平有什么用途？

主要应用于医药中间体及原料药。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Azelnidipine · CAS 123524-52-7 · C33H34N4O6. UNII PV23P19YUG. Melting Point: 193-195; LogP: 5.18.

Identification

CAS Registry Number	123524-52-7
PubChem CID	65948
Molecular formula	C33H34N4O6
IUPAC name	3-O-(1-benzhydrylazetidin-3-yl) 5-O-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
UNII (FDA)	PV23P19YUG

Computed Descriptors

Molecular Weight	582.6
XLogP3	6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	10
Exact Mass	582.24783482
Monoisotopic Mass	582.24783482
Topological Polar Surface Area	140
Heavy Atom Count	43
Formal Charge	0

Physical & Chemical Properties

Melting Point	193-195
LogP	5.18

Physical description & handling notes

Insoluble in water

GHS Hazard Classification

Reported hazard statements	H302 (100%), H318 (95.1%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H318 (95.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

Documented Uses

For the treatment of hypertension.
Oral ingestion of azelnidipine demonstrates rapid and dose-dependent absorption.
In one study, following a single 4mg oral dose of 14C-labeled azelnidipine in humans, about 26% of the drug was thought to br excreted in the urine and 63% in the feces during the 1 week period post administration.
In a Chinese study examining the pharmacokinetics of the drug, the volume of distribution was found to be 1749 +/- 964.
Azelnidipine is widely bound to human plasma proteins (90%–91%).
Like most members of its class, azelnidipine primarily undergoes first-pass hepatic metabolism. Azelnidipine is metabolized by hepatic cytochrome P450 (CYP) 3A4 and has no active metabolite product. It may interact with other drugs or compounds that are substrates for this enzyme. Azelnidipine is lipophilic and has a potent affinity for membranes of vascular smooth muscle cells.

Synonyms

Azelnidipine; 123524-52-7; Calblock; CS-905; DTXSID3020120; Azelnidipino; PV23P19YUG; CS905; DTXCID50120; azelnidipinum; RefChem:560476; Azelnidipine [INN]; CS 905; MFCD00865803; C33H34N4O6; HMS3651D18

Frequently Asked Questions

What are the CAS number and molecular formula of Azelnidipine?

CAS 123524-52-7; molecular formula C33H34N4O6; molecular weight — g/mol.

What other names is Azelnidipine known by?

Azelnidipine, 123524-52-7, Calblock, CS-905, DTXSID3020120, Azelnidipino.

Is Azelnidipine classified as hazardous?

Hazard statements reported: H302, H318.

What are the key physical properties of Azelnidipine?

Melting Point: 193-195; LogP: 5.18.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.