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Alfuzosin

CAS 81403-80-7C19H27N5O4MW 389.4

Alfuzosin (CAS 81403-80-7) — formula C19H27N5O4, molecular weight 389.4; category pharmaceutical intermediates and APIs.

Product Description

Alfuzosin (CAS 81403-80-7) is a chemical raw material in the pharmaceutical intermediates and APIs category. Its molecular formula C19H27N5O4 comprises 19 C, 27 H, 5 N, 4 O atoms. Its molecular weight is about 389.4. Reported physicochemical data: melting point around 240, boiling point around 688, LogP about 1.604. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number81403-80-7
Molecular FormulaC19H27N5O4
Molecular Weight389.4
Melting Point240
Boiling Point688
LogP1.604
ApplicationsMedication: antihypertensive, Use (kg, approx.) in Germany (2009): >250, Consumption (g per capita, approx.) in Germany (2009): 0.00305, Calculated removal (%): 9.2
CategoryPharmaceutical Intermediates & APIs

Applications

Documented applications: Medication: antihypertensive, Use (kg, approx.) in Germany (2009): >250, Consumption (g per capita, approx.) in Germany (2009): 0.00305, Calculated removal (%): 9.2.

Technical Profile

What this product is

Alfuzosin is a pharmaceutical intermediate or API compound with CAS registry number 81403-80-7 and molecular formula C19H27N5O4 (molecular weight 389.4), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.

Identification

CAS number: 81403-80-7

Its molecular formula C19H27N5O4 comprises 19 C, 27 H, 5 N, 4 O atoms.

Also known as: Alfuzosin · 阿夫唑嗪

Category: pharmaceutical intermediates and APIs

Frequently Asked Questions

What is the CAS number of Alfuzosin?

The CAS registry number of Alfuzosin is 81403-80-7.

What is the molecular formula and molecular weight of Alfuzosin?

Molecular formula C19H27N5O4, molecular weight 389.4.

What other names is Alfuzosin known by?

It is also registered under: Alfuzosin, 阿夫唑嗪.

What are the documented applications of Alfuzosin?

Recorded applications: Medication: antihypertensive, Use (kg, approx.) in Germany (2009): >250, Consumption (g per capita, approx.) in Germany (2009): 0.00305, Calculated removal (%): 9.2.

Which category does Alfuzosin belong to?

Category: Pharmaceutical Intermediates & APIs.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Alfuzosin (CAS 81403-80-7), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number81403-80-7
PubChem CID2092
Molecular formulaC19H27N5O4
IUPAC nameN-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]oxolane-2-carboxamide
UNII (FDA)90347YTW5F

Computed descriptors

Molecular Weight389.4
XLogP31.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass389.20630436
Monoisotopic Mass389.20630436
Topological Polar Surface Area112
Heavy Atom Count28

Physicochemical values on record

Boiling Point688
Melting Point240
Solubility2.82e-01 g/L
LogP1.604
LogP1.4
LogP1.93
Dissociation Constants8.13
Dissociation ConstantspKa = 8.13

Documented uses on record

    Use (kg; approx.) in Germany (2009): >250Consumption (g per capita; approx.) in Germany (2009): 0.00305

    Synonyms and trade names

    alfuzosin; 81403-80-7; Alfuzosina; Alfuzosine; Alfuzosinum; NSC-760065; N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}oxolane-2-carboxamide; 90347YTW5F; N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide; DTXSID6048549; CHEBI:51141; alphuzosine; N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide; alfusozine; N-(3-((4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)oxolane-2-carboxamide; N-(3-((4-imino-6,7-dimethoxy-3,4-dihydroquinazolin-2-yl)(methyl)amino)propyl)oxolane-2-carboximidic acid

    GHS hazard classification

    Reported hazard statementsH373 (100%)

    H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

    P260, P319, and P501 (click each P-code to see the statement)

    What the public record says

    Alfuzosin · CAS 81403-80-7 · C19H27N5O4. UNII 90347YTW5F. Boiling Point: 688; Melting Point: 240; Solubility: 2.82e-01 g/L.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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