acemetacin (CAS 53164-05-9) — formula C21H18ClNO6, molecular weight 415.8; category pharmaceutical intermediates and APIs.
acemetacin (CAS 53164-05-9) is a pharmaceutical intermediates and APIs. Its molecular formula C21H18ClNO6 comprises 21 C, 18 H, 1 Cl, 1 N, 6 O atoms. Its molecular weight is about 415.8. Reported physicochemical data: melting point around 151.5ºC, boiling point around 637ºC, LogP about 4.49. Pharmaceutical intermediates and APIs are critical building blocks for drug synthesis, with strict requirements on purity, impurities and process consistency. Used in API synthesis, formulation and pre-clinical research; supplied with COA and impurity-profile documentation. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 53164-05-9 |
|---|---|
| Molecular Formula | C21H18ClNO6 |
| Molecular Weight | 415.8 |
| Melting Point | 151.5ºC |
| Boiling Point | 637ºC |
| LogP | 4.49 |
| Applications | Use (kg, approx.) in Germany (2009): >1000, Consumption (g per capita, approx.) in Germany (2009): 0.0122, Excretion rate: 1, Calculated removal (%): 72.5 |
| Category | Pharmaceutical Intermediates & APIs |
Documented applications: Use (kg, approx.) in Germany (2009): >1000, Consumption (g per capita, approx.) in Germany (2009): 0.0122, Excretion rate: 1, Calculated removal (%): 72.5.
acemetacin is a pharmaceutical intermediate or API compound with CAS registry number 53164-05-9 and molecular formula C21H18ClNO6 (molecular weight 415.8), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 53164-05-9
Its molecular formula C21H18ClNO6 comprises 21 C, 18 H, 1 Cl, 1 N, 6 O atoms.
Also known as: acemetacin · 阿西美辛
Category: pharmaceutical intermediates and APIs
The CAS registry number of acemetacin is 53164-05-9.
Molecular formula C21H18ClNO6, molecular weight 415.8.
It is also registered under: acemetacin, 阿西美辛.
Recorded applications: Use (kg, approx.) in Germany (2009): >1000, Consumption (g per capita, approx.) in Germany (2009): 0.0122, Excretion rate: 1, Calculated removal (%): 72.5.
Category: Pharmaceutical Intermediates & APIs.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for acemetacin (CAS 53164-05-9), compiled from public chemistry databases.
| CAS Registry Number | 53164-05-9 |
|---|---|
| PubChem CID | 1981 |
| Molecular formula | C21H18ClNO6 |
| IUPAC name | 2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl]oxyacetic acid |
| UNII (FDA) | 5V141XK28X |
| Molecular Weight | 415.8 |
|---|---|
| XLogP3 | 4.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 7 |
| Exact Mass | 415.0822650 |
| Monoisotopic Mass | 415.0822650 |
| Topological Polar Surface Area | 94.8 |
| Heavy Atom Count | 29 |
| Boiling Point | 637ºC |
|---|---|
| Melting Point | 151.5ºC |
| LogP | 4.49 |
| Dissociation Constants | 2.6 |
acemetacin; 53164-05-9; Rantudil; Acemix; Emflex; Acemetacina; Acemetacine; Acemetacinum; TVX 3322; K 708; K-708; indomethacin carboxymethyl ester; DTXSID7022540; indometacin glycolic ester; indomethacin glycolic ester; 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, carboxymethyl ester
| Reported hazard statements | H300 (100%), H310 (60%), H330 (60%) |
|---|
H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]
H310 (60%): Fatal in contact with skin [Danger Acute toxicity, dermal]
acemetacin · CAS 53164-05-9 · C21H18ClNO6. UNII 5V141XK28X. Boiling Point: 637ºC; Melting Point: 151.5ºC; LogP: 4.49.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 阿西美辛