胆固醇

Description

Cholesterol · CAS 57-88-5 · C27H46O. UNII 97C5T2UQ7J. Boiling Point: 360; Boiling Point: 360 °C (decomposes); Melting Point: 148.5.

Identification

CAS Registry Number	57-88-5
PubChem CID	5997
Molecular formula	C27H46O
IUPAC name	(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
UNII (FDA)	97C5T2UQ7J

Computed Descriptors

Molecular Weight	386.7
XLogP3	8.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	5
Exact Mass	386.354866087
Monoisotopic Mass	386.354866087
Topological Polar Surface Area	20.2
Heavy Atom Count	28
Formal Charge	0

Physical & Chemical Properties

Boiling Point	360
Boiling Point	360 °C (decomposes)
Melting Point	148.5
Melting Point	148.5 °C
Melting Point	148 °C
Solubility	0.095
Solubility	In water, 0.095 mg/l @ 30 °C.
Solubility	9.5e-05 mg/mL
Density	1.067 @ 20 °C/4 °C
Vapor Pressure	VP: 0.171 mm Hg at 149 °C

Physical description & handling notes

• White or faintly yellow solid; Nearly odorless; [HSDB] Beige solid; [Sigma-Aldrich MSDS]
• Solid
• White or faintly yellow pearly granules or crystals
• Almost odorless
• MP: 145.5 °C (the melt becomes clear at 180 °C); optical rotation (25 °C/D) = -13.7 deg (c = 0.9 in chloroform) /Benzoate/
• Moderately soluble in hot alcohol; soluble in benzene, oils, fats and aq solns of bile salts

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Cosmetic ingredients (Cholesterol) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Stabilizing; Emulsifying; Emollient
GHS notification summary	97.8% (222 / 227)

GHS Hazard Classification

GHS notification summary	97.8% (222 / 227)

Documented Uses

• Main sterol of higher animals found in all body tissues; Used as an emulsifying agent for pharmaceuticals; [Merck Index] Also used as a raw material for syntheses; [HSDB]
• Used in pharmaceutical and dermal preparations as an emulsifying agent.
• ... Important as raw material for syntheses involving microbiological degradation of the side chain.
• Found in many foods (meats, eggs, milk, cheese, fish, shellfish) derived from animal products. Essential for membrane integrity. Used in steroid hormone synthesis.
• Cosmetics -> Stabilizing; Emulsifying; Emollient
• Information on 23 consumer products that contain Cholesterol in the following categories is provided:

Synonyms

cholesterol; 57-88-5; Cholesterin; Cholest-5-en-3beta-ol; Cholesteryl alcohol; Dythol; Cordulan; Dusoline; Dusoran; Cholesterine; Cholestrin; Cholestrol; Hydrocerin; Lidinite; Kathro; Lanol

Frequently Asked Questions

What are the CAS number and molecular formula of Cholesterol?

CAS 57-88-5; molecular formula C27H46O; molecular weight — g/mol.

What other names is Cholesterol known by?

cholesterol, 57-88-5, Cholesterin, Cholest-5-en-3beta-ol, Cholesteryl alcohol, Dythol.

What is the regulatory status of Cholesterol?

Documented regulatory listings: CIR / INCI: Cosmetic ingredients (Cholesterol) -> CIR (Cosmetic Ingredient Review); CIR / INCI: Stabilizing; Emulsifying; Emollient.

Is Cholesterol classified as hazardous?

97.8% of GHS notifications report no hazard classification (222 of 227).

What are the key physical properties of Cholesterol?

Boiling Point: 360; Boiling Point: 360 °C (decomposes); Melting Point: 148.5; Melting Point: 148.5 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.