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Zinc Pyrithione

CAS 13463-41-7C10H8N2O2S2ZnMW 317.7

Zinc Pyrithione (CAS 13463-41-7) — formula C10H8N2O2S2Zn, molecular weight 317.7.

Product Overview

CAS Number13463-41-7
Molecular FormulaC10H8N2O2S2Zn
Molecular Weight317.7
Melting Point240 °C, decomposes
ApplicationsUses: For zinc 2-pyridinethiol-1-oxide (USEPA, OPP Pesticide Code: 088002) ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., In marine antifouling paints, Additive in antidandruff preparations, preservation of cosmetics, metalworking fluids, inhibition of bacterial and fungal growth on fabrics, Zinc pyrithione shampoos are widely used nonprescription formulations that are effective temporarily in treatment of ... seborrheic capitis, For more Uses (Complete) data for Pyrithione zinc (7 total), please visit the HSDB record page., Zinc pyrithione is used as an antifungal and antibacterial agent. (L76), Use Classification: Cosmetics -> Preservative, Antiseborrhoeic, Industry Uses: Other, Preservative, Stabilizing agent, Anti-scaling agent, Consumer Uses: Other, Household Products: Cosmetics product ingredient: Pyrithione zinc (Zinc pyrithione), Product count: 9, Information on 118 consumer products that contain Zinc pyrithione in the following categories is provided:, • Home Maintenance, • Personal Care, Methods of Manufacturing: Derived from 2-chloropyridine N-oxide., Formulations, Preparations: Ecostern (PPG Industries, Zinc 2-pyridinethiol-1-oxide 4.8%, E Paint ZO (E Paint), HMF Antifouling Paint (Sherwin-Williams), Zinc 2-pyridinethiol-1-oxide 6.38%, 1H-Pyrrole-3-carbonitrile, 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)- 7.28%, Intersmooth 360 Ecoloflex SPC Antifouling BEA 368 Dark Brown (International Paint), Zinc 2-pyridinethiol-1-oxide 3.8%, Copper(I) oxide 40.41%, For more Formulations, Preparations (Complete) data for Pyrithione zinc (17 total), U.S. Production: 2023: 75, 000 - <100, 000 lb, 2022: 250, 000 - <400, 2021: 100, 000 - <250, 2020: 50, Zinc, bis[1-(hydroxy-.kappa.O)-2(1H)-pyridinethionato-.kappa.S2]-, (T-4)- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438).[EPA, Office of Pollution Prevention and Toxics, High Production Volume (HPV) Challenge Program. Zinc, bis, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4971], [US EPA, Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Zinc, General Manufacturing Information: Textiles, apparel, and leather manufacturing, All Other Chemical Product and Preparation Manufacturing, Paint and Coating Manufacturing, (T-4)-: ACTIVE, RED Addendum scheduled for June 2010 ... Docket No. EPA-HQ-OPP-2004-0147, Antimicrobial effect was studied with healthy scalps in relation to its antidandruff effect. Use of Zn pyrithione containing shampoo sharply decr the corneocyte counts.

Applications

Documented applications: Uses: For zinc 2-pyridinethiol-1-oxide (USEPA, OPP Pesticide Code: 088002) ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., In marine antifouling paints, Additive in antidandruff preparations, preservation of cosmetics, metalworking fluids, inhibition of bacterial and fungal growth on fabrics, Zinc pyrithione shampoos are widely used nonprescription formulations that are effective temporarily in treatment of ... seborrheic capitis, For more Uses (Complete) data for Pyrithione zinc (7 total), please visit the HSDB record page., Zinc pyrithione is used as an antifungal and antibacterial agent. (L76), Use Classification: Cosmetics -> Preservative, Antiseborrhoeic, Industry Uses: Other, Preservative, Stabilizing agent, Anti-scaling agent, Consumer Uses: Other, Household Products: Cosmetics product ingredient: Pyrithione zinc (Zinc pyrithione), Product count: 9, Information on 118 consumer products that contain Zinc pyrithione in the following categories is provided:, • Home Maintenance, • Personal Care, Methods of Manufacturing: Derived from 2-chloropyridine N-oxide., Formulations, Preparations: Ecostern (PPG Industries, Zinc 2-pyridinethiol-1-oxide 4.8%, E Paint ZO (E Paint), HMF Antifouling Paint (Sherwin-Williams), Zinc 2-pyridinethiol-1-oxide 6.38%, 1H-Pyrrole-3-carbonitrile, 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)- 7.28%, Intersmooth 360 Ecoloflex SPC Antifouling BEA 368 Dark Brown (International Paint), Zinc 2-pyridinethiol-1-oxide 3.8%, Copper(I) oxide 40.41%, For more Formulations, Preparations (Complete) data for Pyrithione zinc (17 total), U.S. Production: 2023: 75, 000 - <100, 000 lb, 2022: 250, 000 - <400, 2021: 100, 000 - <250, 2020: 50, Zinc, bis[1-(hydroxy-.kappa.O)-2(1H)-pyridinethionato-.kappa.S2]-, (T-4)- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438).[EPA, Office of Pollution Prevention and Toxics, High Production Volume (HPV) Challenge Program. Zinc, bis, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4971], [US EPA, Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Zinc, General Manufacturing Information: Textiles, apparel, and leather manufacturing, All Other Chemical Product and Preparation Manufacturing, Paint and Coating Manufacturing, (T-4)-: ACTIVE, RED Addendum scheduled for June 2010 ... Docket No. EPA-HQ-OPP-2004-0147, Antimicrobial effect was studied with healthy scalps in relation to its antidandruff effect. Use of Zn pyrithione containing shampoo sharply decr the corneocyte counts..

Technical Profile

What this product is

Zinc Pyrithione is a chemical compound with CAS registry number 13463-41-7 and molecular formula C10H8N2O2S2Zn (molecular weight 317.7).

Identification

CAS number: 13463-41-7

Its molecular formula C10H8N2O2S2Zn comprises 10 C, 8 H, 2 N, 2 O, 2 S, 1 Zn atoms.

Also known as: Zinc Pyrithione · 吡啶硫酮锌 · shampoo

Frequently Asked Questions

What is the CAS number of Zinc Pyrithione?

The CAS registry number of Zinc Pyrithione is 13463-41-7.

What is the molecular formula and molecular weight of Zinc Pyrithione?

Molecular formula C10H8N2O2S2Zn, molecular weight 317.7.

What other names is Zinc Pyrithione known by?

It is also registered under: Zinc Pyrithione, 吡啶硫酮锌, shampoo.

What are the documented applications of Zinc Pyrithione?

Recorded applications: Uses: For zinc 2-pyridinethiol-1-oxide (USEPA, OPP Pesticide Code: 088002) ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., In marine antifouling paints, Additive in antidandruff preparations, preservation of cosmetics, metalworking fluids, inhibition of bacterial and fungal growth on fabrics, Zinc pyrithione shampoos are widely used nonprescription formulations that are effective temporarily in treatment of ... seborrheic capitis, For more Uses (Complete) data for Pyrithione zinc (7 total), please visit the HSDB record page., Zinc pyrithione is used as an antifungal and antibacterial agent. (L76), Use Classification: Cosmetics -> Preservative, Antiseborrhoeic, Industry Uses: Other, Preservative, Stabilizing agent, Anti-scaling agent, Consumer Uses: Other, Household Products: Cosmetics product ingredient: Pyrithione zinc (Zinc pyrithione), Product count: 9, Information on 118 consumer products that contain Zinc pyrithione in the following categories is provided:, • Home Maintenance, • Personal Care, Methods of Manufacturing: Derived from 2-chloropyridine N-oxide., Formulations, Preparations: Ecostern (PPG Industries, Zinc 2-pyridinethiol-1-oxide 4.8%, E Paint ZO (E Paint), HMF Antifouling Paint (Sherwin-Williams), Zinc 2-pyridinethiol-1-oxide 6.38%, 1H-Pyrrole-3-carbonitrile, 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)- 7.28%, Intersmooth 360 Ecoloflex SPC Antifouling BEA 368 Dark Brown (International Paint), Zinc 2-pyridinethiol-1-oxide 3.8%, Copper(I) oxide 40.41%, For more Formulations, Preparations (Complete) data for Pyrithione zinc (17 total), U.S. Production: 2023: 75, 000 - <100, 000 lb, 2022: 250, 000 - <400, 2021: 100, 000 - <250, 2020: 50, Zinc, bis[1-(hydroxy-.kappa.O)-2(1H)-pyridinethionato-.kappa.S2]-, (T-4)- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438).[EPA, Office of Pollution Prevention and Toxics, High Production Volume (HPV) Challenge Program. Zinc, bis, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4971], [US EPA, Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Zinc, General Manufacturing Information: Textiles, apparel, and leather manufacturing, All Other Chemical Product and Preparation Manufacturing, Paint and Coating Manufacturing, (T-4)-: ACTIVE, RED Addendum scheduled for June 2010 ... Docket No. EPA-HQ-OPP-2004-0147, Antimicrobial effect was studied with healthy scalps in relation to its antidandruff effect. Use of Zn pyrithione containing shampoo sharply decr the corneocyte counts..

PubChem Public Data

Independent reference data for Zinc Pyrithione (CAS 13463-41-7), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number13463-41-7
PubChem CID26041
Molecular formulaC10H8N2O2S2Zn
IUPAC namezinc bis(1-oxidopyridin-1-ium-2-thiolate)

Computed descriptors

Molecular Weight317.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass315.931862
Monoisotopic Mass315.931862
Topological Polar Surface Area52.9
Heavy Atom Count17

Physicochemical values on record

Melting Point240 °C, decomposes
Density1.782 at 25 °C
Stability/Shelf LifeStable at 100 °C for 120 hr

Documented uses on record

    Additive in antidandruff preparations, preservation of cosmetics, metalworking fluids, inhibition of bacterial and fungal growth on fabricsZinc pyrithione shampoos are widely used nonprescription formulations that are effective temporarily in treatment of ... seborrheic capitis

    Synonyms and trade names

    DTXSID7026314; DTXCID90820451; Zinc pt; Finecide ZPT; Hokucide ZPT; Niccanon SKT; Biocut ZP; Tomicide Z 50; Tomicide ZPT 50; Evafine P 50; 2-Mercaptopyridine 1-oxide zinc salt; biokera; shampoo; bis(N-oxopyridine-2-thionato)zinc (II); Vegetability; Balancing

    Regulatory listings held on file

    Regulatory & Food ContactFDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS
    The FCS is intended for use as an antimicrobial active ingredient for preservation of the components of paper
    Zinc pyrithione (CAS Reg. No. 13463-41-7) <strong>REPLACES FCN 2031</strong>
    The FCS is intended for use as an antimicrobial agent to inhibit the growth of bacteria on the surface of poly
    The FCS is intended for use:
    * As an antimicrobial agent for preservation of the components of paper coatings (non-polymeric substrates) us
    GHS notification summary0.4% (5 / 1321)

    GHS hazard classification

    GHS notification summary0.4% (5 / 1321)
    Reported hazard statementsH301, H318, H330, H372, H400, H410, H302 (16.4%), H331 (55%)

    H301: Toxic if swallowed [Danger Acute toxicity, oral]

    H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]

    What the public record says

    shampoo · CAS 13463-41-7 · C10H8N2O2S2Zn. Melting Point: 240 °C, decomposes; Density: 1.782 at 25 °C; Stability/Shelf Life: Stable at 100 °C for 120 hr.

    Physical description and handling notes

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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