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Description

Cinchonine · CAS 118-10-5 · C19H22N2O. UNII V43X79NZCD. LogP: 2.68.

Identification

CAS Registry Number	118-10-5
PubChem CID	90454
Molecular formula	C19H22N2O
IUPAC name	(S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
UNII (FDA)	V43X79NZCD

Computed Descriptors

Molecular Weight	294.4
XLogP3	2.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	294.173213330
Monoisotopic Mass	294.173213330
Topological Polar Surface Area	36.4
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

LogP	2.68

Physical description & handling notes

• 165.21 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 168.69 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 169.65 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 161.3 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 166.3 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (100%), H317 (29.2%), H332 (63.1%)

Documented Uses

• Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)

Synonyms

cinchonine; 118-10-5; D-Cinchonine; (9S)-Cinchonan-9-ol; Cinchonan-9-ol, (9S)-; (8R,9S)-Cinchonine; (+)-Cinconine; DTXSID6045082; NSC-6176; V43X79NZCD; CHEBI:27509; DTXCID801474963; 2-Quinuclidinemethanol, alpha-(5-vinyl-2-quinolyl)-; alpha-(5-Vinyl-2-quinuclidinyl)-4-quinolinemethanol; (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol; (S)-((2R,4S,5R)-5-ethenyl-1-azabicyclo(2.2.2)octan-2-yl)-quinolin-4-ylmethanol

Frequently Asked Questions

What are the CAS number and molecular formula of Cinchonine?

CAS 118-10-5; molecular formula C19H22N2O; molecular weight — g/mol.

What other names is Cinchonine known by?

cinchonine, 118-10-5, D-Cinchonine, (9S)-Cinchonan-9-ol, Cinchonan-9-ol, (9S)-, (8R,9S)-Cinchonine.

Is Cinchonine classified as hazardous?

Hazard statements reported: H302, H317, H332.

What are the key physical properties of Cinchonine?

LogP: 2.68.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.