o-Methylanisole

Description

o-Methylanisole is identified by CAS 578-58-5, molecular formula C8H10O and molecular weight 122.07 g/mol. UNII 09G73SL17K; ChEBI 141702; InChIKey DTFKRVXLBCAIOZ-UHFFFAOYSA-N. Boiling Point: 170.00 to 172.00 °C. @ 760.00 mm Hg; Boiling Point: 172 °C; Melting Point: -34.1 °C.

Identification

CAS Registry Number	578-58-5
PubChem CID	33637
Molecular formula	C8H10O
Molecular weight	122.07 g/mol
IUPAC name	1-methoxy-2-methylbenzene
InChIKey	DTFKRVXLBCAIOZ-UHFFFAOYSA-N
UNII (FDA)	09G73SL17K
ChEBI ID	CHEBI:141702
FEMA number	2680
JECFA number	1242

Computed Descriptors

Molecular Weight	122.16
XLogP3	2.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	122.073164938
Monoisotopic Mass	122.073164938
Topological Polar Surface Area	9.2
Heavy Atom Count	9
Formal Charge	0

Physical & Chemical Properties

Boiling Point	170.00 to 172.00 °C. @ 760.00 mm Hg
Boiling Point	172 °C
Melting Point	-34.1 °C
Density	0.983-0.986 (15.5 °C)
Vapor Pressure	1.5 [mmHg]
LogP	2.74
Refractive Index	1.518-1.522 (15.3 °C)

Physical description & handling notes

• Colorless liquid with a pleasant odor; [Alfa Aesar MSDS]
• Liquid
• Colourless liquid, Pungent-floral, warm, but almost grassy note
• Insoluble in water, soluble in oils
• soluble (in ethanol)

Regulatory Status

Regulatory & Food Contact	EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Flower, Walnut, Warm No safety concern at current levels of intake when used as a flavouring agent
GHS notification summary	0.8% (11 / 1453)

GHS Hazard Classification

GHS notification summary	0.8% (11 / 1453)
Reported hazard statements	H226 (10.7%), H302 (88.6%)

Documented Uses

• Used as flavoring agent or adjuvant; [FDA]
• Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
• Flavoring Agents -> JECFA Flavorings Index
• Benzene, 1-methoxy-2-methyl-: ACTIVE

Synonyms

2-Methylanisole; 578-58-5; 1-Methoxy-2-methylbenzene; o-Methylanisole; 2-Methoxytoluene; o-Methoxytoluene; o-Cresol methyl ether; BENZENE, 1-METHOXY-2-METHYL-; o-Cresyl methyl ether; Methyl o-tolyl ether; Anisole, o-methyl-; 2-Methylmethoxybenzene; Methyl o-cresyl ether; FEMA No. 2680; 09G73SL17K; NSC-6253

Frequently Asked Questions

What are the CAS number and molecular formula of o-Methylanisole?

CAS 578-58-5; molecular formula C8H10O; molecular weight 122.07 g/mol.

What other names is o-Methylanisole known by?

2-Methylanisole, 578-58-5, 1-Methoxy-2-methylbenzene, o-Methylanisole, 2-Methoxytoluene, o-Methoxytoluene.

What is the regulatory status of o-Methylanisole?

Documented regulatory listings: EU Flavoring substances; FDA Substance added to food: FLAVORING AGENT OR ADJUVANT; Flavoring Agents.

Is o-Methylanisole classified as hazardous?

0.8% of GHS notifications report no hazard classification (11 of 1453).

What are the key physical properties of o-Methylanisole?

Boiling Point: 170.00 to 172.00 °C. @ 760.00 mm Hg; Boiling Point: 172 °C; Melting Point: -34.1 °C; Density: 0.983-0.986 (15.5 °C).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.