谷胱甘肽

Description

Glutathione is identified by CAS 70-18-8, molecular formula C10H17N3O6S and molecular weight 307.08 g/mol. UNII GAN16C9B8O; ChEBI 16856; InChIKey RWSXRVCMGQZWBV-WDSKDSINSA-N. Melting Point: 195; Melting Point: 195 °C; Solubility: 292.5 mg/mL.

Identification

CAS Registry Number	70-18-8
PubChem CID	124886
Molecular formula	C10H17N3O6S
Molecular weight	307.08 g/mol
IUPAC name	(2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
InChIKey	RWSXRVCMGQZWBV-WDSKDSINSA-N
UNII (FDA)	GAN16C9B8O
ChEBI ID	CHEBI:16856
ATC code (WHO)	V03AB32

Computed Descriptors

Molecular Weight	307.33
XLogP3	-4.5
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	9
Exact Mass	307.08380644
Monoisotopic Mass	307.08380644
Topological Polar Surface Area	160
Heavy Atom Count	20
Formal Charge	0

Physical & Chemical Properties

Melting Point	195
Melting Point	195 °C
Solubility	292.5 mg/mL
LogP	-6.4
Collision Cross Section	167.9 Ų [M+H]+
Collision Cross Section	162.8 Ų [M-H]-
Collision Cross Section	164.8 Ų [M-2H+Na]-
Collision Cross Section	167.1 Ų [M+Na]+

Physical description & handling notes

• Solid; [Merck Index] White powder; [Sigma-Aldrich MSDS]
• Solid
• 166.87 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 163.44 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 161.18 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 164.59 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

Regulatory & Food Contact	Ingredient in several food categories, including meat products, at levels ranging from 5 to 300 milligrams per Scientific procedures At the notifier's request, FDA ceased to evaluate this notice Kohjin Co., Ltd. FDA has no questions
GHS notification summary	82.5% (47 / 57)

GHS Hazard Classification

GHS notification summary	82.5% (47 / 57)
Reported hazard statements	H341 (15.8%)

Documented Uses

• Main low molecular weight thiol found in living plant and animal cells; [Merck Index] A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides. [ChemIDplus]
• For nutritional supplementation, also for treating dietary shortage or imbalance
• Glycine, L-.gamma.-glutamyl-L-cysteinyl-: ACTIVE
• V03 - All other therapeutic products
• V03A - All other therapeutic products
• QV03 - All other therapeutic products

Synonyms

glutathione; 70-18-8; L-Glutathione reduced; L-Glutathione; Glutathion; Isethion; reduced glutathione; Glutinal; Tathion; Glutathione-SH; Deltathione; Copren; Neuthion; Tathione; Glutide; Triptide

Frequently Asked Questions

What are the CAS number and molecular formula of Glutathione?

CAS 70-18-8; molecular formula C10H17N3O6S; molecular weight 307.08 g/mol.

What other names is Glutathione known by?

glutathione, 70-18-8, L-Glutathione reduced, L-Glutathione, Glutathion, Isethion.

What is the regulatory status of Glutathione?

Documented regulatory listings: Ingredient in several food categories, including meat products, at levels ranging from 5 to 300 milligrams per; Scientific procedures; At the notifier's request, FDA ceased to evaluate this notice.

Is Glutathione classified as hazardous?

82.5% of GHS notifications report no hazard classification (47 of 57).

What are the key physical properties of Glutathione?

Melting Point: 195; Melting Point: 195 °C; Solubility: 292.5 mg/mL; LogP: -6.4.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.