氯唑西林钠（CAS 7081-44-9）：分子式 C19H18ClN3O5S、分子量 435.9。
| CAS号 | 7081-44-9 |
|---|---|
| 分子式 | C19H18ClN3O5S |
| 分子量 | 435.9 |
| LogP | 2.48 |
| 应用领域 | Uses: MEDICATION、Methods of Manufacturing: 6-Aminopenicillanic acid is acylated with 3-(o-chlorophenyl)-5- methyl-4-isoxazolecarboxylic acid and the resulting cloxacillin (acid) is purified by recrystallizations and converted to the sodium salt、Sodium Cloxacillin USP、General Manufacturing Information: NOT RECOMMENDED IN US FOR USE IN FOOD PRODUCING ANIMALS.、MORE RECENTLY INTRODUCED SEMISYNTHETIC DERIVATIVES OF PENICILLIN... CLOXACILLIN...SIMILAR IN ACTION TO PARENT COMPD BUT SOME ARE ALSO EFFECTIVE AGAINST...PENICILLINASE PRODUCING STAPHYLOCOCCI.、PENICILLINS、...SAFE TO ASSUME THAT AFTER...RECOMMENDED OR NON-RECOMMENDED USAGE FDA INSISTS TO ZERO TOLERANCE FOR DRUG IN EDIBLE TISSUES OF ANIMALS & POULTRY INCLUDING THEIR BY-PRODUCTS、MILK、OR EGGS DESTINED FOR HUMAN USE...CURRENTLY PERMITTING 0.05 PPM FOR ITS NEGLIGIBLE RESIDUE IN UNCOOKED EDIBLE TISSUES OF CATTLE.、PROPERTIES & PHARMACOLOGY: NAYLOR ET AL、NATURE 195、1264 (1962). |
登记用途：Uses: MEDICATION、Methods of Manufacturing: 6-Aminopenicillanic acid is acylated with 3-(o-chlorophenyl)-5- methyl-4-isoxazolecarboxylic acid and the resulting cloxacillin (acid) is purified by recrystallizations and converted to the sodium salt、Sodium Cloxacillin USP、General Manufacturing Information: NOT RECOMMENDED IN US FOR USE IN FOOD PRODUCING ANIMALS.、MORE RECENTLY INTRODUCED SEMISYNTHETIC DERIVATIVES OF PENICILLIN... CLOXACILLIN...SIMILAR IN ACTION TO PARENT COMPD BUT SOME ARE ALSO EFFECTIVE AGAINST...PENICILLINASE PRODUCING STAPHYLOCOCCI.、PENICILLINS、...SAFE TO ASSUME THAT AFTER...RECOMMENDED OR NON-RECOMMENDED USAGE FDA INSISTS TO ZERO TOLERANCE FOR DRUG IN EDIBLE TISSUES OF ANIMALS & POULTRY INCLUDING THEIR BY-PRODUCTS、MILK、OR EGGS DESTINED FOR HUMAN USE...CURRENTLY PERMITTING 0.05 PPM FOR ITS NEGLIGIBLE RESIDUE IN UNCOOKED EDIBLE TISSUES OF CATTLE.、PROPERTIES & PHARMACOLOGY: NAYLOR ET AL、NATURE 195、1264 (1962).。
氯唑西林钠 是一种化工化合物，登记 CAS 号为 7081-44-9，分子式 C19H18ClN3O5S（分子量 435.9）。
登记 CAS 号：7081-44-9
其分子式 C19H18ClN3O5S 由 19 个碳、18 个氢、1 个氯、3 个氮、5 个氧、1 个硫 组成。
别名/同义词：氯唑西林钠 · Sodium cloxacillin monohydrate
氯唑西林钠 的 CAS 登记号为 7081-44-9。
分子式 C19H18ClN3O5S，分子量 435.9。
别名/同义词：氯唑西林钠、Sodium cloxacillin monohydrate。
登记用途：Uses: MEDICATION、Methods of Manufacturing: 6-Aminopenicillanic acid is acylated with 3-(o-chlorophenyl)-5- methyl-4-isoxazolecarboxylic acid and the resulting cloxacillin (acid) is purified by recrystallizations and converted to the sodium salt、Sodium Cloxacillin USP、General Manufacturing Information: NOT RECOMMENDED IN US FOR USE IN FOOD PRODUCING ANIMALS.、MORE RECENTLY INTRODUCED SEMISYNTHETIC DERIVATIVES OF PENICILLIN... CLOXACILLIN...SIMILAR IN ACTION TO PARENT COMPD BUT SOME ARE ALSO EFFECTIVE AGAINST...PENICILLINASE PRODUCING STAPHYLOCOCCI.、PENICILLINS、...SAFE TO ASSUME THAT AFTER...RECOMMENDED OR NON-RECOMMENDED USAGE FDA INSISTS TO ZERO TOLERANCE FOR DRUG IN EDIBLE TISSUES OF ANIMALS & POULTRY INCLUDING THEIR BY-PRODUCTS、MILK、OR EGGS DESTINED FOR HUMAN USE...CURRENTLY PERMITTING 0.05 PPM FOR ITS NEGLIGIBLE RESIDUE IN UNCOOKED EDIBLE TISSUES OF CATTLE.、PROPERTIES & PHARMACOLOGY: NAYLOR ET AL、NATURE 195、1264 (1962).。
氯唑西林钠（CAS 7081-44-9）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 7081-44-9 |
|---|---|
| PubChem CID | 6098 |
| 分子式 | C19H18ClN3O5S |
| IUPAC 名称 | (2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| UNII（FDA） | O6X5QGC2VB |
| Molecular Weight | 435.9 |
|---|---|
| XLogP3 | 2.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 4 |
| Exact Mass | 435.0655696 |
| Monoisotopic Mass | 435.0655696 |
| Topological Polar Surface Area | 138 |
| Heavy Atom Count | 29 |
| Solubility | 5.32e-02 g/L |
|---|---|
| LogP | 2.48 |
| LogP | LogP = 2.44 |
| LogP | 2.86 |
| Dissociation Constants | 2.78 |
| Collision Cross Section | 200.94 Ų [M-H]- |
cloxacillin; 61-72-3; Cloxacilline; Cloxacillinum; Cloxacilina; Methocillin S; Syntarpen; Clossacillina; Chloroxacillin; O6X5QGC2VB; (3-(o-Chlorophenyl)-5-methyl-4-isoxazolyl)penicillin; CHEBI:49566; 6-(3-(o-Chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid; cloxacillina; Cloxacillin, Sodium; Sodium, Cloxacillin
| 已通报的危害声明 | H315 (85.4%), H317 (91.7%), H319 (85.4%), H334 (97.9%), H335 (85.4%) |
|---|
氯唑西林钠 · CAS 7081-44-9 · C19H18ClN3O5S. UNII O6X5QGC2VB. Solubility: 5.32e-02 g/L; LogP: 2.48; LogP: LogP = 2.44.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Sodium cloxacillin monohydrate