活性红180（CAS 72828-03-6）：分子式 C19H23N5O3、分子量 369.4。
| CAS号 | 72828-03-6 |
|---|---|
| 分子式 | C19H23N5O3 |
| 分子量 | 369.4 |
| 熔点 | 215-217 °C |
| LogP | 2.5 |
| 应用领域 | Uses: MEDICATION、For use、with concurrent leucovorin administration (leucovorin protection)、as an alternative therapy for the treatment of moderate-to-severe <i>Pneumocystis carinii<、i> pneumonia (PCP) in immunocompromised patients、including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer.、General Manufacturing Information: Lipophilic dihydrofolate reductase structurally related to methotrexate、with antimicrobial and antitumor activity. |
登记用途：Uses: MEDICATION、For use、with concurrent leucovorin administration (leucovorin protection)、as an alternative therapy for the treatment of moderate-to-severe <i>Pneumocystis carinii<、i> pneumonia (PCP) in immunocompromised patients、including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer.、General Manufacturing Information: Lipophilic dihydrofolate reductase structurally related to methotrexate、with antimicrobial and antitumor activity.。
活性红180 是一种化工化合物，登记 CAS 号为 72828-03-6，分子式 C19H23N5O3（分子量 369.4）。
登记 CAS 号：72828-03-6
其分子式 C19H23N5O3 由 19 个碳、23 个氢、5 个氮、3 个氧 组成。
别名/同义词：活性红180 · Reactive Red 180
活性红180 的 CAS 登记号为 72828-03-6。
分子式 C19H23N5O3，分子量 369.4。
别名/同义词：活性红180、2,7-Naphthalenedisulfonic acid, 5-(benzoylamino)-4-hydroxy-3-1-sulfo-6-2-(sulfooxy)ethylsulfonyl-2-naphthalenylazo-, tetrasodium salt。
登记用途：Uses: MEDICATION、For use、with concurrent leucovorin administration (leucovorin protection)、as an alternative therapy for the treatment of moderate-to-severe <i>Pneumocystis carinii<、i> pneumonia (PCP) in immunocompromised patients、including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer.、General Manufacturing Information: Lipophilic dihydrofolate reductase structurally related to methotrexate、with antimicrobial and antitumor activity.。
活性红180（CAS 72828-03-6）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 72828-03-6 |
|---|---|
| PubChem CID | 5583 |
| 分子式 | C19H23N5O3 |
| IUPAC 名称 | 5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline-2,4-diamine |
| UNII（FDA） | UPN4ITI8T4 |
| Molecular Weight | 369.4 |
|---|---|
| XLogP3 | 2.5 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 6 |
| Exact Mass | 369.18008961 |
| Monoisotopic Mass | 369.18008961 |
| Topological Polar Surface Area | 118 |
| Heavy Atom Count | 27 |
| Melting Point | 215-217 °C |
|---|---|
| Melting Point | 215 - 217 °C |
| Solubility | 31.4 |
| Solubility | 3.09e-02 g/L |
| Solubility | Water 1 - 2 (mg/mL) |
| Solubility | 0.1NHC1 1 - 5 (mg/mL) |
| Solubility | 0.1 N NaOH < 1 (mg/mL) |
| Solubility | Methanol 12 - 15 (mg/mL) |
| Solubility | 95% Ethanol 1 - 5 (mg/mL) |
| Solubility | 10% Ethanol 1 - 3 (mg/mL) |
trimetrexate; 52128-35-5; Trimetrexato; Trimetrexatum; NSC-249008; NSC 249008; UPN4ITI8T4; DTXSID3023714; 5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}quinazoline-2,4-diamine; NSC249008; 2,4-Diamino-5-methyl-6-((3,4,5-trimethoxyanilino)methyl)quinazoline; 5-Methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-2,4-quinazolinediamine; 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)quinazoline-2,4-diamine; 2,4-Quinazolinediamine, 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-; 5-methyl-6-[[(3,4,5-trimethoxyphenyl)amino]methyl]quinazoline-2,4-diamine; 2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline
活性红180 · CAS 72828-03-6 · C19H23N5O3. UNII UPN4ITI8T4. Melting Point: 215-217 °C; Melting Point: 215 - 217 °C; Solubility: 31.4.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Reactive Red 180