脱氢角鲨烯

脱氢角鲨烯（CAS 11051-27-7）：分子式 C30H50、分子量 410.7。

产品概览

应用领域

登记用途：Uses: CIR ingredient: Squalene、Present in large quantities in shark liver oil、and in minute amounts in olive oil、wheat germ oil、rice bran oil、and yeast、An intermediate in the biosynthesis of cholesterol、Used as a bactericide、and as an intermediate for pharmaceuticals、organic coloring agents、rubber chemicals、aromatics、and surface active agents、[Merck Index] Also used in biochemical and pharmaceutical research、[NTP]、Bactericide、intermediate in manufacture of pharmaceuticals、organic coloring materials、aromatics and surface active agents.、Biochemical and pharmaceutical research、a percursor of cholestrol in biosynthesis、chemical intermediate.、Squalane and Squalene have been identified as natural components of human sebum. Both ingredients are used in a variety of cosmetics at concentrations ranging from < or =0.1 to >50%.、Squalene is a polyunsaturated hydrocarbon with a formula of C30H50. Squalene can be found in certain fish oils、especially shark liver oil、in high amounts and some vegetable oils in relatively smaller amounts. Human sebum also contains 13% squalene as one of its major constituents. Squalane is a saturated derivative of squalene and also found in these sources. Interest in squalene has been raised after its characterization in shark liver oil which is used as a traditional medicine for decades. Several studies exhibited results that prove certain bioactivities for squalene and squalane. Up to date、anticancer、antioxidant、drug carrier、detoxifier、skin hydrating、and emollient activities of these substances have been reported both in animal models and in vitro environments. According to promising results from recent studies、squalene and squalane are considered important substances in practical and clinical uses with a huge potential in nutraceutical and pharmaceutical industries.、For more Uses (Complete) data for Squalene (9 total)、please visit the HSDB record page.、Use Classification: Fragrance Ingredients、Cosmetics -> Hair conditioning、Refatting、Emollient、Antistatic、Household Products: Information on 1 consumer products that contain Squalene in the following categories is provided:、• Personal Care、Methods of Manufacturing: Squalene is commercially extracted from fish oil、and in particular shark liver oil. Squalene used in pharmaceutical products and vaccines is purified from this source.、Commercially available methods for squalene extraction from olive oil yield to a vegetable squalene with around 97.5% purity、while squalene obtained from shark liver oil can reach 99.9% purity.、Squalene is extracted from shark liver or synthesized from hexaphenyl-1、4-butanediyldiphosphonium dibromide and 6、10-dimethyl-5、9-undecadien-2-one (geranylacetone、industrial intermediate in the vitamin E synthesis).、General Manufacturing Information: 2、6、10、14、18、22-Tetracosahexaene、2、15、19、23-hexamethyl-、(6E、10E、14E、18E)-: ACTIVE、Squalene is a liquid that is available in capsules for oral use. Doses of 500 milligrams to 4 grams are used、the higher doses are used by some cancer、patients、. The source of squalene is usually from shark liver and sometimes from olive oil.、Squalene、a 30-carbon isoprenoid、is a lipid found in large quantities in shark liver and in smaller amounts (0.1 to 0.7%) in olive oil、rice bran oil and yeast.、Squalene was discovered in 1906 by the Japanese researcher Dr. Mitsumaru Tsujimoto、an expert in oils and fats at Tokyo Industrial Testing Station. He separated the unsaponifiable fraction from the shark liver oil "kurokozame" and discovered the existence of a highly unsaturated hydrocarbon. Ten years later、Tsujimoto succeeded to obtain by fractional vacuum of the liver oil from two deep-sea shark species an unsaturated hydrocarbon、with the chemical formula C30H50、which he named "squalene". The name came from the denomination of the sharks' family: Squalidae.、In the case of deep-sea sharks、the liver is the main organ for lipids' storage、being in the same time an energy source and means for adjusting the buoyancy. In their case、the unsaponifiable matter represents 50-80% of the liver、the great majority thereof being squalene. For example、Centrophorus artomarginatus deep-sea sharks which live in waters at 600 to 1000m depth、without sunlight、manage to survive where pressure is consistently high and the oxygen supply is very poor、due to this compound from their liver、which accounts for 25% to 30% of their total body weight. The liver of the shark Centrophorus squamosus represents 18.1% from the body mass、77.2% by weight of the liver composition is oil and the squalene concentration in this oil is 79.6%. Similar values have been obtained for Centroscymnus crepidater. An interesting discovery has been made-squalene can be found in higher amounts not only in the liver of some shark species but also in other organs thereof.、For more General Manufacturing Information (Complete) data for Squalene (7 total)。

技术档案

这个产品是什么

脱氢角鲨烯 是一种化工化合物，登记 CAS 号为 11051-27-7，分子式 C30H50（分子量 410.7）。

识别信息

登记 CAS 号：11051-27-7

其分子式 C30H50 由 30 个碳、50 个氢 组成。

别名/同义词：脱氢角鲨烯 · dehydrosqualene

常见问题

PubChem 公开数据