L-Leucine（CAS 61-90-5）：分子式 C6H13NO2、分子量 131.17。
| CAS号 | 61-90-5 |
|---|---|
| 分子式 | C6H13NO2 |
| 分子量 | 131.17 |
| 熔点 | 293 |
| LogP | -1.52 |
| 应用领域 | Uses: CIR ingredient: Leucine、An essential amino acid、[Merck Index] Used as a flavoring agent and nutritional supplement for foods、[FDA] Used in biochemical research、[HSDB]、Nutrient and dietary supplement、biochemical research、Nutrient、BIOLOGICAL ACTIVITY: Antiencephalopathic、Reported uses、Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#7497]、Indicated to assist in the prevention of the breakdown of muscle proteins that sometimes occur after trauma or severe stress.、Use Classification: EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives、Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Cosmetics -> Skin conditioning、Antistatic、Hair conditioning、Industry Uses: Catalyst、Consumer Uses: Catalyst、Methods of Manufacturing: Hydrolysis of protein (edestin、hemoglobin、zein)、organic synthesis from the alpah-bromo acid.、By bromination followed by amination of isocaproic acid、via the acetamidomalonic ester、by isolation from gluten、casein、keratin、from hydantoin.、Impurities: Heavy metals (as Pb): not more than 0.002%、Lead: not more than 10 mg、kg、Ash: not more than 0.1%、U.S. Production: 2023: 41、827 lb、2022: 53、668 lb、2021: 74、021 lb、2020: 58、051 lb、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7496]、General Manufacturing Information: Pharmaceutical and Medicine Manufacturing、L-Leucine: ACTIVE、Leucine: ACTIVE、The amino acids that are incorporated into mammalian protein are alpha-amino acids、with the exception of proline、which is an alpha-imino acid. This means that they have a carboxyl group、an amino nitrogen group、and a side chain attached to a central alpha-carbon. Functional differences among the amino acids lie in the structure of their side chains. In addition to differences in size、these side groups carry different charges at physiological pH (e.g.、nonpolar、uncharged but polar、negatively charged、positively charged)、some groups are hydrophobic (e.g.、branched chain and aromatic amino acids) and some hydrophilic (most others). These side chains have an important bearing on the ways in which the higher orders of protein structure are stabilized and are intimate parts of many other aspects of protein function. |
登记用途：Uses: CIR ingredient: Leucine、An essential amino acid、[Merck Index] Used as a flavoring agent and nutritional supplement for foods、[FDA] Used in biochemical research、[HSDB]、Nutrient and dietary supplement、biochemical research、Nutrient、BIOLOGICAL ACTIVITY: Antiencephalopathic、Reported uses、Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#7497]、Indicated to assist in the prevention of the breakdown of muscle proteins that sometimes occur after trauma or severe stress.、Use Classification: EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives、Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Cosmetics -> Skin conditioning、Antistatic、Hair conditioning、Industry Uses: Catalyst、Consumer Uses: Catalyst、Methods of Manufacturing: Hydrolysis of protein (edestin、hemoglobin、zein)、organic synthesis from the alpah-bromo acid.、By bromination followed by amination of isocaproic acid、via the acetamidomalonic ester、by isolation from gluten、casein、keratin、from hydantoin.、Impurities: Heavy metals (as Pb): not more than 0.002%、Lead: not more than 10 mg、kg、Ash: not more than 0.1%、U.S. Production: 2023: 41、827 lb、2022: 53、668 lb、2021: 74、021 lb、2020: 58、051 lb、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7496]、General Manufacturing Information: Pharmaceutical and Medicine Manufacturing、L-Leucine: ACTIVE、Leucine: ACTIVE、The amino acids that are incorporated into mammalian protein are alpha-amino acids、with the exception of proline、which is an alpha-imino acid. This means that they have a carboxyl group、an amino nitrogen group、and a side chain attached to a central alpha-carbon. Functional differences among the amino acids lie in the structure of their side chains. In addition to differences in size、these side groups carry different charges at physiological pH (e.g.、nonpolar、uncharged but polar、negatively charged、positively charged)、some groups are hydrophobic (e.g.、branched chain and aromatic amino acids) and some hydrophilic (most others). These side chains have an important bearing on the ways in which the higher orders of protein structure are stabilized and are intimate parts of many other aspects of protein function.。
L-Leucine 是一种化工化合物，登记 CAS 号为 61-90-5，分子式 C6H13NO2（分子量 131.17）。
登记 CAS 号：61-90-5
其分子式 C6H13NO2 由 6 个碳、13 个氢、1 个氮、2 个氧 组成。
别名/同义词：L-Leucine
L-Leucine 的 CAS 登记号为 61-90-5。
分子式 C6H13NO2，分子量 131.17。
别名/同义词：L-Leucine。
登记用途：Uses: CIR ingredient: Leucine、An essential amino acid、[Merck Index] Used as a flavoring agent and nutritional supplement for foods、[FDA] Used in biochemical research、[HSDB]、Nutrient and dietary supplement、biochemical research、Nutrient、BIOLOGICAL ACTIVITY: Antiencephalopathic、Reported uses、Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#7497]、Indicated to assist in the prevention of the breakdown of muscle proteins that sometimes occur after trauma or severe stress.、Use Classification: EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives、Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Cosmetics -> Skin conditioning、Antistatic、Hair conditioning、Industry Uses: Catalyst、Consumer Uses: Catalyst、Methods of Manufacturing: Hydrolysis of protein (edestin、hemoglobin、zein)、organic synthesis from the alpah-bromo acid.、By bromination followed by amination of isocaproic acid、via the acetamidomalonic ester、by isolation from gluten、casein、keratin、from hydantoin.、Impurities: Heavy metals (as Pb): not more than 0.002%、Lead: not more than 10 mg、kg、Ash: not more than 0.1%、U.S. Production: 2023: 41、827 lb、2022: 53、668 lb、2021: 74、021 lb、2020: 58、051 lb、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7496]、General Manufacturing Information: Pharmaceutical and Medicine Manufacturing、L-Leucine: ACTIVE、Leucine: ACTIVE、The amino acids that are incorporated into mammalian protein are alpha-amino acids、with the exception of proline、which is an alpha-imino acid. This means that they have a carboxyl group、an amino nitrogen group、and a side chain attached to a central alpha-carbon. Functional differences among the amino acids lie in the structure of their side chains. In addition to differences in size、these side groups carry different charges at physiological pH (e.g.、nonpolar、uncharged but polar、negatively charged、positively charged)、some groups are hydrophobic (e.g.、branched chain and aromatic amino acids) and some hydrophilic (most others). These side chains have an important bearing on the ways in which the higher orders of protein structure are stabilized and are intimate parts of many other aspects of protein function.。
L-Leucine（CAS 61-90-5）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 61-90-5 |
|---|---|
| PubChem CID | 6106 |
| 分子式 | C6H13NO2 |
| 分子量 | 131.09 g/mol |
| IUPAC 名称 | (2S)-2-amino-4-methylpentanoic acid |
| InChIKey | ROHFNLRQFUQHCH-YFKPBYRVSA-N |
| UNII（FDA） | GMW67QNF9C |
| ChEBI 编号 | CHEBI:15603 |
| FEMA 编号 | 3297 |
| JECFA 编号 | 1423 |
| Molecular Weight | 131.17 |
|---|---|
| XLogP3 | -1.5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Exact Mass | 131.094628657 |
| Monoisotopic Mass | 131.094628657 |
| Topological Polar Surface Area | 63.3 |
| Heavy Atom Count | 9 |
| Melting Point | 293 |
|---|---|
| Melting Point | 293 °C |
| Melting Point | 268 - 288 °C |
| Solubility | 21500 |
| Solubility | In water, 2.15X10+4 mg/L at 25 °C |
| Solubility | 21.5 mg/mL |
| Density | 1.293 g/cu cm at 18 °C |
| Vapor Pressure | 0.00000001 [mmHg] |
| LogP | -1.52 |
| LogP | log Kow = -1.52 |
L-leucine; 61-90-5; leucine; (S)-2-Amino-4-methylpentanoic acid; (S)-Leucine; (2S)-2-amino-4-methylpentanoic acid; (S)-(+)-Leucine; Leucin; (S)-2-Amino-4-methylvaleric acid; L-alpha-Aminoisocaproic acid; LEUCINE, L-; Leucinum; Leucina; FEMA No. 3297; (2S)-alpha-leucine; L-leucin
| 法规与食品接触 | EU Flavoring substances FDA Substance added to food: FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent 非奶和奶基代餐、运动饮料和等渗饮料、维生素强化水的成分 Scientific procedures |
|---|---|
| GHS 通报统计 | 100% (208 / 208) |
| GHS 通报统计 | 100% (208 / 208) |
|---|
L-Leucine 的 CAS 号为 61-90-5，分子式 C6H13NO2，分子量 131.09 g/mol。 UNII GMW67QNF9C; ChEBI 15603; InChIKey ROHFNLRQFUQHCH-YFKPBYRVSA-N. Melting Point: 293; Melting Point: 293 °C; Melting Point: 268 - 288 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: L-Leucine