硫酸长春碱（CAS 143-67-9）：分子式 C46H58N4O9、分子量 811.0。
| CAS号 | 143-67-9 |
|---|---|
| 分子式 | C46H58N4O9 |
| 分子量 | 811.0 |
| 熔点 | 267 |
| LogP | 3.7 |
| 应用领域 | Uses: For treatment of breast cancer、testicular cancer、lymphomas、neuroblastoma、Hodgkin's and non-Hodgkin's lymphomas、mycosis fungoides、histiocytosis、and Kaposi's sarcoma.、... in the treatment of Hodgkins disease、Vinblastine sulfate USP、THERAP CAT: Antineoplastic、MEDICATION (VET)、MEDICATION、For treatment of breast cancer、Methods of Manufacturing: ... Isolated from periwinkle、Vinca rosea Linn、Apocynaceae.、BY EXTRACTING LEAVES、BARK、OR STEMS OF VINCA ROSEA ... ISOLATING ALKALOID ... BY PRECIPITATION & SOLVENT TECHNIQUES、& PURIFYING BY CHROMATOGRAPHY ... CONVERSION TO (1:1) SULFATE ... BY DISSOLVING ALKALOID IN EQUIMOLAR QUANTITY OF DILUTE SULFURIC ACID & ... EVAPORATING TO DRYNESS OR PRECIPITATING WITH SUITABLE ORG SOLVENT.、VINBLASTINE SULFATE、Vinblastine and vincristine occur in Catharanthus roseus (L). The plant contains only very small amounts of vinblastine and vincristine、and their isolation is correspondingly difficult. First the alkaloids present are separated by extraction into alkaloid tartrate soluble in benzene and alkaloid tartrates insoluble in benzene. Vinblastine and vincristine belong to the first group. They then are separated by chromatography on aluminum oxide deactivated with acetic acid.、Formulations、Preparations: Parenteral Injection、for IV use only 1 mg、mL、Vinblastine Sulfate Injection (with benzyl alcohol 0.9%)、Abraxis、Sterile、for IV use only 10 mg、Bedford、Vials、10 mg、Vinblastine sulfate、General Manufacturing Information: VINBLASTINE IS CLASS II IMMUNOSUPPRESSIVE DRUG、BUT IT HAS NOT BEEN EXPLOITED FOR THIS PURPOSE.、Antitumor alkaloid |
登记用途：Uses: For treatment of breast cancer、testicular cancer、lymphomas、neuroblastoma、Hodgkin's and non-Hodgkin's lymphomas、mycosis fungoides、histiocytosis、and Kaposi's sarcoma.、... in the treatment of Hodgkins disease、Vinblastine sulfate USP、THERAP CAT: Antineoplastic、MEDICATION (VET)、MEDICATION、For treatment of breast cancer、Methods of Manufacturing: ... Isolated from periwinkle、Vinca rosea Linn、Apocynaceae.、BY EXTRACTING LEAVES、BARK、OR STEMS OF VINCA ROSEA ... ISOLATING ALKALOID ... BY PRECIPITATION & SOLVENT TECHNIQUES、& PURIFYING BY CHROMATOGRAPHY ... CONVERSION TO (1:1) SULFATE ... BY DISSOLVING ALKALOID IN EQUIMOLAR QUANTITY OF DILUTE SULFURIC ACID & ... EVAPORATING TO DRYNESS OR PRECIPITATING WITH SUITABLE ORG SOLVENT.、VINBLASTINE SULFATE、Vinblastine and vincristine occur in Catharanthus roseus (L). The plant contains only very small amounts of vinblastine and vincristine、and their isolation is correspondingly difficult. First the alkaloids present are separated by extraction into alkaloid tartrate soluble in benzene and alkaloid tartrates insoluble in benzene. Vinblastine and vincristine belong to the first group. They then are separated by chromatography on aluminum oxide deactivated with acetic acid.、Formulations、Preparations: Parenteral Injection、for IV use only 1 mg、mL、Vinblastine Sulfate Injection (with benzyl alcohol 0.9%)、Abraxis、Sterile、for IV use only 10 mg、Bedford、Vials、10 mg、Vinblastine sulfate、General Manufacturing Information: VINBLASTINE IS CLASS II IMMUNOSUPPRESSIVE DRUG、BUT IT HAS NOT BEEN EXPLOITED FOR THIS PURPOSE.、Antitumor alkaloid。
硫酸长春碱 是一种化工化合物，登记 CAS 号为 143-67-9，分子式 C46H58N4O9（分子量 811.0）。
登记 CAS 号：143-67-9
其分子式 C46H58N4O9 由 46 个碳、58 个氢、4 个氮、9 个氧 组成。
别名/同义词：硫酸长春碱 · Vinblastine sulfate
硫酸长春碱 的 CAS 登记号为 143-67-9。
分子式 C46H58N4O9，分子量 811.0。
别名/同义词：硫酸长春碱、Vinblastine sulfate。
登记用途：Uses: For treatment of breast cancer、testicular cancer、lymphomas、neuroblastoma、Hodgkin's and non-Hodgkin's lymphomas、mycosis fungoides、histiocytosis、and Kaposi's sarcoma.、... in the treatment of Hodgkins disease、Vinblastine sulfate USP、THERAP CAT: Antineoplastic、MEDICATION (VET)、MEDICATION、For treatment of breast cancer、Methods of Manufacturing: ... Isolated from periwinkle、Vinca rosea Linn、Apocynaceae.、BY EXTRACTING LEAVES、BARK、OR STEMS OF VINCA ROSEA ... ISOLATING ALKALOID ... BY PRECIPITATION & SOLVENT TECHNIQUES、& PURIFYING BY CHROMATOGRAPHY ... CONVERSION TO (1:1) SULFATE ... BY DISSOLVING ALKALOID IN EQUIMOLAR QUANTITY OF DILUTE SULFURIC ACID & ... EVAPORATING TO DRYNESS OR PRECIPITATING WITH SUITABLE ORG SOLVENT.、VINBLASTINE SULFATE、Vinblastine and vincristine occur in Catharanthus roseus (L). The plant contains only very small amounts of vinblastine and vincristine、and their isolation is correspondingly difficult. First the alkaloids present are separated by extraction into alkaloid tartrate soluble in benzene and alkaloid tartrates insoluble in benzene. Vinblastine and vincristine belong to the first group. They then are separated by chromatography on aluminum oxide deactivated with acetic acid.、Formulations、Preparations: Parenteral Injection、for IV use only 1 mg、mL、Vinblastine Sulfate Injection (with benzyl alcohol 0.9%)、Abraxis、Sterile、for IV use only 10 mg、Bedford、Vials、10 mg、Vinblastine sulfate、General Manufacturing Information: VINBLASTINE IS CLASS II IMMUNOSUPPRESSIVE DRUG、BUT IT HAS NOT BEEN EXPLOITED FOR THIS PURPOSE.、Antitumor alkaloid。
硫酸长春碱（CAS 143-67-9）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 143-67-9 |
|---|---|
| PubChem CID | 13342 |
| Molecular formula | C46H58N4O9 |
| UNII (FDA) | 5V9KLZ54CY |
| Molecular Weight | 811.0 |
|---|---|
| XLogP3 | 3.7 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 12 |
| Rotatable Bond Count | 10 |
| Exact Mass | 810.42037944 |
| Monoisotopic Mass | 810.42037944 |
| Topological Polar Surface Area | 154 |
| Heavy Atom Count | 59 |
| Melting Point | 267 |
|---|---|
| Melting Point | 211-216 °C |
| LogP | 3.7 |
| LogP | log Kow = 3.70 |
| LogP | 3.72 |
| Dissociation Constants | pKa1 = 5.4; pKa2 = 7.4 |
vinblastine; 865-21-4; Vinblastin; Vincaleucoblastin; Vinblastina; Vincoblastine; Vincaleukoblastine; Nincaluicolflastine; Vinblastinum; Vincaleucoblastine; NCI-C04842; 5V9KLZ54CY; NSC 47842; NDC 0002-1452-01; NSC-47842; (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE
Vinblastine sulfate · CAS 143-67-9 · C46H58N4O9. UNII 5V9KLZ54CY. Melting Point: 267; Melting Point: 211-216 °C; LogP: 3.7.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Vinblastine sulfate