Tetracosactide

Description

Tetracosactide · CAS 16960-16-0 · C136H210N40O31S. UNII 72YY86EA29.

Identification

Computed Descriptors

Physical description & handling notes

• Specific optical rotation: -88 +/- 2 deg at 22 °C/D (c = 0.511 in 1% acetic acid). UV max (0.1 NaOH): 283, 289 nm (epsilon 8550, 8810) /Cosyntropin hexacetate/
• Parenteral: for injection 0.25 mg Cortrosyn (with mannitol) (Organon).
• IM injection: 1 mg/mL, 1 mL ampoules; containers of 1, Synacthen Depot (Novartis Pharmaceuticals Australia Pty Ltd)

GHS Hazard Classification

Documented Uses

• THERAPEUTIC CATEGORY: Diagnostic aid (adrenal function)
• THERAPEUTIC CATEGORY (VET): Diagnostic aid (adrenal function)
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Synthetic polypeptide corresponding to the first 24 amino acids of ACTH
• For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
• Investigationally, long-acting IM depot cosyntropin preparations have been used as an aid in the diagnosis of adrenocortical insufficiency and, in patients with normal adrenocortical function, in the long-term management of chronic inflammatory and degenerative disorders that are responsive to glucocorticoids. /NOT included in US product label/

Synonyms

Tetracosactide; COSYNTROPIN; Tetracosapeptide; Cortrosyn; Tetracosactid; Actholain; Synacthen; 16960-16-0; Tetracosactrin; Tetracosactida; Synthetic ACTH; Tetracosactide hexacetate; 1-24-Corticotropin; CHEBI:3901; ((2S,3R,4S)-2,3,4,5-tetrahydroxypentyl) dihydrogen phosphate; [(2S,3R,4S)-2,3,4,5-tetrahydroxypentyl] dihydrogen phosphate

Frequently Asked Questions

What are the CAS number and molecular formula of Tetracosactide?

CAS 16960-16-0; molecular formula C136H210N40O31S; molecular weight — g/mol.

What other names is Tetracosactide known by?

Tetracosactide, COSYNTROPIN, Tetracosapeptide, Cortrosyn, Tetracosactid, Actholain.

Is Tetracosactide classified as hazardous?

Hazard statements reported: H317, H332, H334.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.